Quantitative
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Clinically Aligned Geometry Constraints for Robust IVUS Vessel Boundary Segmentation
2026-08-27 01:24:28Yunshu Chen, Litao Yang, Giuseppe Di Giovanni, Jordan Tan, Deval Mehta, Andrew Lin, Derek Chew, Masasi Fujino, Julie Butters, Stephen Nicholls, Zongyuan Ge, Kyung Hoon ChoAbstract
Intravascular ultrasound (IVUS) lumen and external elastic membrane (EEM) segmentation is important for quantitative coronary plaque burden assessment. Errors in lumen or EEM delineation directly propagate to plaque area, plaque burden and geometric measurements. However, standard methods prioritising overlap scores often suffer from boundary drift and topology errors, leading to inaccurate clinical measurements. We present GeoCat, a geometry-consistent network that processes 5-frame IVUS clips using dual Cartesian-polar encoders with cross-domain attention and temporal fusion. A differentiable geometry consistency loss directly supervises clinically relevant descriptors including diameters, orientations, and cross-sectional areas. The model is trained on 12,242 annotated frames from 146 patients acquired with two commercial IVUS systems. We evaluate performance using both segmentation accuracy and plaque-relevant clinical metrics, including Dice/IoU, boundary measures(95HD (mm), ASSD), topology violation rate, and clinical geometry errors (dmax/dmin, angles, and areas). On our dataset, GeoCat achieves a Dice of 0.93, reduces 95HD to 0.14 mm, and lowers topology violations to 1.0%. Importantly, it significantly improves geometric fidelity, yielding diameter errors of 0.13-0.16 mm and angular errors of ~8 degrees, supporting reliable plaque burden quantification.
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URL
https://arxiv.org/abs/2606.18723
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Neuro-symbolic PRM: Enhancing Scientific Reasoning via Structured Traces and Symbolic Verification
2026-08-26 19:10:12Yuxin Zi, Cong Xu, Suparna Bhattacharya, Martin Foltin, Amit ShethAbstract
While tool-augmented Large Language Models have significantly improved multi-step reasoning in quantitative STEM tasks, a critical residual failure mode remains: intermediate reasoning steps that are syntactically well-formed, mathematically executable, and unit-consistent, yet contextually ungrounded. Current approaches either rely on formal verifiers that cannot assess semantic intent, or burden Process Reward Models (PRMs) with the dual task of checking both arithmetic and logic. In this paper, we propose a neuro-symbolic framework that cleanly decouples reasoning into two formal dimensions: Symbolic Validity ($V$) and Semantic Groundedness ($G$). We guarantee $V$ by construction using a deterministic symbolic verifier acting as a hard filter. To assess $G$, we train a PRM conditionally on the verifier-accepted manifold. To train this PRM efficiently, we introduce Counterfactual Symbolic Perturbation (CSP), a novel data synthesis strategy that algorithmically generates constraint-preserving hard negatives (steps that perfectly pass the verifier but are logically flawed). At inference, we deploy a verifier-first constrained search that guarantees execution consistency for verifier-covered operations while relying on the PRM solely to rank semantic grounding. By targeting the exact residual error class of strong tool-using LLMs, our method significantly improves reasoning reliability without the sprawling heuristics of prior frameworks.
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URL
https://arxiv.org/abs/2608.26329
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6.5% of the Neuro-Symbolic Literature Can Be Reproduced from Its Published Artifacts, a Six-Stage Audit Framework and First Instantiation
2026-08-26 17:48:17Brandon Colelough, Vladimir Martirosyan, Ishan Tamrakar, William Regli, Aditya Kumar, Anh N. Nhu, Dhruv Dubey, Raj Ambavane, Haowei DengAbstract
We present a six-stage framework for auditing the reproducibility of scientific claims across a research literature within the computer science domain, and instantiate our framework for the neuro-symbolic AI (NSAI) subdomain. Instantiating the framework on the NSAI subdomain produced a multi-year audit. Stage one retrieved 5,497 records and removed 3,018 duplicates. Stage two screened the 2,479 unique records at title and abstract, identifying 1,365 self-identified NSAI records, then removed a further 61 at full text for off-topic, non-research, no-quantitative-evaluation, or inaccessible-full-text reasons. Stage three sought a verifiable public code artifact for each of the 1,304 eligible records and found none for 849, leaving 455 to enter the artifact inventory and bounded rerun of stages four and five. We fully or partially reproduced 85 studies, 6.52% of the eligible corpus and 18.68% of attempted reruns. We found that 321 attempted reruns were blocked by missing non- code artifacts and 42 by missing or unusable code repositories. These figures quantify a persistent reproducibility deficit that survives even nominal "code available" declarations, and signal the need for enforced, versioned, and permanently archived artifact bundles in future NSAI publications. We argue that empirical NSAI papers should be required at submission time to provide complete, versioned, and permanently archived artifact bundles.
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https://arxiv.org/abs/2608.26236
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A Statistical Audit of Physical AI Benchmark Redundancy
2026-08-26 15:54:15Zaruhi Navasardyan, Hrant DavtyanAbstract
Physical AI models are evaluated on suites of benchmarks that differ across model reports, leaving the model-by-benchmark matrix sparse and the relationship between benchmarks unmeasured. We construct a matrix of 51 models on 12 physical AI benchmarks, selected from a registry of 51 benchmarks and 152 models by reporting density, combining scores from model cards and benchmark papers with our own evaluation runs under each benchmark's official protocol. We measure how much information the benchmarks share and show quantitative evidence of Redundancy. Redundancy affects reported rankings: collapsing the two substitute pairs into single columns moves 22 of 51 models by three or more places under an equally weighted average. We then select benchmarks greedily under a utility combining score dispersion with variance not explained by the already-selected set, and obtain a four-benchmark subset retaining 78.5\% of the utility of all 12, on which we fit a Bradley--Terry ranking. The procedure requires only benchmark-level scores with sufficient overlap and is not specific to physical AI.
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URL
https://arxiv.org/abs/2608.25940
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Steer the Sampling, Not the Kernel Grid: Geometry-Guided Sampling Operator for Volumetric Segmentation
2026-08-26 14:01:36Sizhe Wang, Himashi Peiris, Zhaolin ChenAbstract
Accurate 3D segmentation is central to quantitative lesion assessment and anatomy mapping for clinical planning and follow-up. Thin, elongated, and fine anatomical/pathological structures (e.g., vessels) are a particularly challenging case: a one-voxel boundary error can disconnect a branch and change clinically relevant topology. In encoder-decoder networks (e.g., U-Net), repeated downsampling and fixed-grid convolution blur or alias fine structures and weaken orientation cues, so early mistakes propagate across scales. We propose a geometry-guided local operator that steers where features are sampled, rather than deforming convolutional kernels, under a single formulation for both feature refinement (stride 1) and resolution reduction (stride > 1). At each voxel, it predicts a local orientation and bounded step sizes, samples symmetrically along these directions, and transforms paired samples into compact geometric and boundary cues with lightweight mixing; a cross-scale consensus aligns encoder and decoder features at skip connections to reduce geometric mismatch. Replacing all stride 1 and stride 2 operators in a 3D U-Net yields consistent improvements on BraTS, MSD Hepatic Vessel, and TDSC-ABUS, with notably better boundary metrics (e.g., BraTS Dice 86.1 to 88.9, HD95 7.1 to 6.2; TDSC-ABUS HD95 39.1 to 27.8) while reducing parameters from 2.3M to 0.8M. We further demonstrate that the operator can be integrated into other backbones (e.g., nnU-Net, Swin-UNETR, and MedNeXt) without changing their macro-architectures while providing consistent performance gains.
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URL
https://arxiv.org/abs/2608.25819
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Learning from waste: Machine Learning for health risk prediction and computer vision-based sorting in Ghana
2026-08-26 13:06:35Hilda Adwubi Osei, Catherine Tenewaa Osei, Desdemona Yaa AsobayireAbstract
The inappropriate disposal of solid waste remains a significant public health and environmental concern worldwide, including in Ghana. Poor sanitation and improper waste management practices contribute to substantial economic costs and avoidable deaths annually. In 2022, a field study in Atonsu, Kumasi, Ghana, reported a community-perceived relationship between household waste disposal and illness patterns, but only through descriptive analysis without quantitative validation. This study extends that investigation using two data-driven approaches. First, a Random Forest classifier was developed to predict illness categories using waste disposal practices and demographic survey data. On a held-out group of respondents who reported illness (N=69), the model obtained a macro F1 score of 0.63, with disposal method emerging as the most important substantive predictor of illness type. Second, a MobileNetV2 image classification model enabled automated waste sorting via visual recognition, achieving 88.2% accuracy and a macro F1 score of 0.87 on the test set (N=415). The vision-based approach offers an affordable, camera-driven alternative to complex multi-sensor systems, making it highly suitable for resource-constrained settings. Taken together, the findings provide quantitative evidence for a community health relationship previously documented only qualitatively. They demonstrate the potential for automated waste-sorting in low-resource environments. Importantly, the results illustrate that technological performance alone does not guarantee public health improvements; effective institutional support and implementation are equally necessary.
Abstract (translated)
URL
https://arxiv.org/abs/2608.25759
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Surgical Video Generation From Diffusion to World Models: A Survey
2026-08-26 08:27:20Fuxiang Huang, Chenxu Zhang, Liang Han, Lei ZhangAbstract
Surgical video data provides the primary training resource for models of intraoperative perception, surgical workflow understanding, and robotic decision-making. However, clinical data acquisition remains constrained by privacy, cost, and class imbalance. Surgical video generation has emerged as a transformative approach to addressing data scarcity and as a foundation for surgical simulation, training, and robotic policy learning. The field has developed rapidly without a clear conceptual framework. This survey organizes the 2024-2026 literature into three categories: unconditional generation, conditional generation, and world modeling generation, revealing a fundamental shift in how the task is defined from synthesizing visually plausible frames to modeling the causal dynamics of surgical scenes. We examine the persistent gap between pixel-level fidelity and clinical plausibility, and identify generalization, physical realism, controllability, and interpretability as bottlenecks. We further summarize experimental results of representative methods on public datasets to provide a quantitative reference for the field. This survey provides a structured overview of the current state and open challenges, offering a reference for researchers working at the intersection of intelligent perception, multi-modal fusion, generative AI, and surgical data science.
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URL
https://arxiv.org/abs/2608.26214
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FlashNormal: Detailed Surface Normal Estimation from Flash and No-Flash Images
2026-08-26 04:34:08Ruiyang Chen, Feiran Li, Heng Guo, Zhanyu MaAbstract
High-quality surface normal estimation is preferred for detailed surface shape recovery and image editing. Existing single image-based methods, though being a practical setup, often struggle to recover fine surface details and are sensitive to inherent shape-reflectance ambiguity. While photometric stereo achieves high-fidelity surface normal estimation from images under varying lights, its applicability is strictly limited by requiring a multi-illumination capture setup. To this end, we propose FlashNormal, a diffusion-based surface normal estimator from flash/no-flash image pairs. While retaining high practicability on modern smartphones, our proposal takes advantage of flash-induced shading variations, and leverages curvature-guided detail enhancement strategy, improving surface detail recovery and mitigating shape-reflectance ambiguity effectively. To evaluate our proposed method, we further present EvalFlash, the first real-world flash/no-flash evaluation dataset containing 20 objects aligned with ground-truth surface normals for quantitative benchmarking. Extensive experiments demonstrate the effectiveness of FlashNormal over state-of-the-art single image-based methods and show a significant out-performance over flash/no-flash-based normal estimation method on EvalFlash.
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URL
https://arxiv.org/abs/2608.25360
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Improving Cross-Site Whole-Heart Segmentation
2026-08-25 20:03:53Tanish Mudaliar, Justin Li, Daniel Lin, Julianna Vo, Kaitao Liao, Xin Wang, Shu HuAbstract
Whole-heart segmentation from CT and MRI is essential for quantitative cardiac image analysis, but remains challenging under multi-center and multi-modality distribution shift. In the CARE whole-heart segmentation task, models must generalize from limited labeled sites to unseen acquisition distributions, where variation in spacing, intensity, reconstruction texture, and anatomy can degrade out-of-distribution performance. We propose a modality-routed 3D cardiac segmentation pipeline that combines TotalSegmentator-initialized nnU-Netv2 models with site-characterized, label-preserving appearance augmentation. We first characterize the available sites using measurable image properties and use this analysis to motivate candidate data-space generalization routes. The final retained recipe applies Bias Field + Bezier appearance augmentation, combining smooth spatial intensity perturbation with nonlinear intensity remapping, followed by lightweight class-wise largest-connected-component cleanup. On the primary held-out-site validation splits, the final configuration improves CT mean Dice from 0.8350 to 0.9135 and MRI mean Dice from 0.7695 to 0.7830, while also reducing HD95. These results suggest that site-motivated appearance augmentation is a practical strategy for improving cross-site robustness in limited-data whole-heart segmentation. Our code can be found in this https URL
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URL
https://arxiv.org/abs/2608.25109
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MoE-based Feature Adapter for Prompt-free Binary Coronary Artery Segmentation in X-ray Angiography
2026-08-25 16:24:53Lin Xi, Yingliang MaAbstract
Accurate segmentation of coronary arteries in X-ray angiography videos is essential for quantitative coronary analysis and image-guided interventions. However, accurate segmentation remains challenging because coronary vessels are thin and exhibit low contrast, while the presence of catheters, guidewires, and complex anatomical background structures can further interfere with vessel delineation. Existing U-Net- and Transformer-based models provide strong baselines, but their shared feature-adaptation pathways may be insufficient for heterogeneous angiographic appearances. In this paper, we propose a prompt-free mixture-of-experts (MoE) feature adapter for binary coronary artery segmentation. Built upon parameter-efficient Vision Transformer adapters, the proposed method uses multiple lightweight experts with input-dependent top-$k$ routing to adaptively refine vessel-related features while limiting active computational cost. Experiments on MOSXAV and external evaluation on XACV show that the proposed method outperforms representative baselines and improves cross-dataset generalisation. These results suggest that MoE-based adapter learning is effective for robust coronary artery segmentation in X-ray angiography videos.
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URL
https://arxiv.org/abs/2608.24783
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Interpretable Fundus Image Classification via Ring-Based Retinal Vasculature Features
2026-08-25 15:37:28Xiaoyan Li, Shixin Xu, Arvind Gupta, Huaxiong HuangAbstract
Retinal fundus photography is widely used for screening and monitoring ocular diseases, but many modern classification pipelines rely on deep latent representations and provide limited interpretability. This study develops an interpretable fundus image classification framework based on a ring-structured representation of the retinal vasculature centered on the optic disc. The method quantifies vessel geometry, color appearance, oxygenation-related vascular appearance, and vessel--background entropy within concentric retinal regions. These physiologically motivated descriptors are derived from vessel masks, image intensities, and optical-density measurements and aggregated across rings to capture spatial variation in vascular properties. Using only quantitative vascular descriptors, the proposed method achieved strong classification performance across three public fundus datasets. On HRF, it achieved 91.1\% accuracy using automatically generated vessel masks, matching RETFound, a vision transformer pretrained on large-scale retinal fundus image data, under the same evaluation setting. Additional analyses suggest that pretrained image models are sensitive to acquisition-related spatial cues, including fundus scale and retinal position within the field of view, as well as broader non-vessel image characteristics. This framework may support interpretable disease classification, quantitative retinal phenotyping, and retinal biomarker discovery without requiring large task-specific training datasets.
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URL
https://arxiv.org/abs/2608.24723
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Towards Reliable AI-Based Histological Staining: A Systematic Study of Scaling and Uncertainty in Unpaired Generative Models
2026-08-25 14:41:57Qasim Siddiqui, Adrian Friebel, Maiju Myllys, Zaynab Hobloss, Daniela Gonzalez, Ahmed Ghallab, Stefan HoehmeAbstract
Liver fibrosis, the principal predictor of long-term outcome in chronic liver disease, is staged from histological estimates of collagen content. Sirius Red (SR) provides the standard quantitative readout (collagen proportionate area, CPA) but is not acquired at every clinical centre and consumes tissue, time, and reagent cost beyond the routine Hematoxylin and eosin (H&E) stain. AI-based virtual staining can generate SR directly from H&E, yet systematic benchmarks of unsupervised models are scarce and their predictive uncertainty has not been quantified, even though visually plausible outputs may not faithfully reproduce the underlying tissue structure. We therefore benchmark six unsupervised image-to-image architectures (GAN-based and diffusion-based) across 54 scaling configurations on a newly released paired H&E to SR mouse liver dataset, the first open resource for this translation task. Each configuration is evaluated jointly on perceptual, distributional, and task-specific axes plus a blinded expert reader study; the best per family is then retrained as a deep ensemble, the first systematic comparison of epistemic uncertainty across unsupervised stain-to-stain architectures. Across families, perceptual quality, task-specific error, and ensemble agreement measure largely independent axes of model fitness: GAN-based methods cluster tightly on perceptual metrics yet differ substantially on task error and ensemble agreement, while the diffusion-based method (CycleDiffusion) is qualitatively different on all three. No single metric captures these differences, so reliable virtual staining requires reporting and selecting on all three jointly. The dataset, tiling pipeline, models, and evaluation code are released publicly.
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URL
https://arxiv.org/abs/2608.24626
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Comparative Assessment of Deep Learning Architectures for Underwater Subsurface Kelp Forest Segmentation with The Kelp-o-Tron
2026-08-25 14:18:40Sundarabalan Balasubramanian, C\'esar Borja, Ana C. Murillo, Lexi N. Wilkes, Meredith L. McPherson, Kira A. Krumhansl, Jennifer A. Dijkstra, Jarrett E. K. ByrnesAbstract
Submerged kelp forests are vital coastal ecosystems that support marine biodiversity and ecosystem dynamics, yet accurate underwater kelp segmentation remains challenging due to optical degradation, illumination variability, turbidity, overlapping vegetation, and complex benthic backgrounds. We systematically evaluated three deep learning semantic segmentation frameworks, ResNet34-U-Net, ResNet50-DeepLabV3, and a hybrid ResNet50-ASPP-Transformer architecture, for kelp detection using high-resolution underwater RGB imagery collected from northeastern U.S. coastal waters. A dataset of 3,395 SSeg assisted annotated image-mask pairs was developed for model training and validation, while geographically independent sites were used for quantitative and qualitative evaluation. All models used consistent preprocessing, augmentation, and evaluation protocols. On independent test data, ResNet50-DeepLabV3 achieved the highest Dice (0.7120) and Intersection over Union (IoU; 0.6267), followed by ResNet34 U Net (Dice 0.6868; IoU 0.5978). The hybrid ASPP Transformer achieved the highest pixel accuracy (0.8528) but lower Dice (0.6437) and IoU (0.5746). External qualitative evaluation further showed that DeepLabV3 produced more consistent segmentation across varying environmental conditions, image qualities, and benthic habitats. Overall, ResNet50-DeepLabV3, termed Kelp-O-Tron, provided the best balance of segmentation accuracy, robustness, and generalization. The dataset, annotation workflow, and comparative evaluation provide resources for advancing automated underwater habitat mapping and ecological monitoring.
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URL
https://arxiv.org/abs/2608.24594
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Human-Inspired Social Engagement Analysis via Interpretable Mutual Visual Attention
2026-08-25 14:05:35Urwa Fatima, Mohammad Zohaib, Francesca Odone, Nicoletta NocetiAbstract
Understanding social interactions from non-verbal visual data is important for behavior analysis and activity monitoring. We propose an interpretable computational model of social engagement inspired by psychological theories of mutual visual attention. Rather than learning interaction patterns end-to-end, our framework explicitly models dyadic visual attention and aggregates these cues into interpretable measures of individual and group engagement. The resulting modular framework combines state-of-the-art head orientation estimation with lightweight geometric reasoning, producing explanations that remain accessible to non-technical users. We evaluate the proposed approach on a variety of data through quantitative experiments and demonstrate its practical usefulness with qualitative visualizations designed to support teachers, caregivers, and social workers in understanding group interaction dynamics.
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URL
https://arxiv.org/abs/2608.24580
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MRI-based Deep Radiomic Phenotyping of Neuromuscular Disorders: A Topology-driven Characterization
2026-08-25 11:30:17Martyna \.Zur, {\L}ukasz Pi\'orecki, Marek Socha, Jordi Diaz-Manera, Jose Verdu Diaz, Volker Straub, Rossella Tupler, Joanna Pola\'nskaAbstract
Quantitative assessment of muscle MRI is crucial for monitoring neuromuscular disorders (NMD). This study introduces an automated radiomic phenotyping framework based on original features engineered across five main architectural domains: quantitative morphometry, spatial distribution, geometric shape, interactions between progressive fat replacement stages, and graph-based topology. Utilizing 1184 MRI scans from the CoMPaSS-NMD project, we map the complex 3D architecture of heterogeneous intramuscular lipodegeneration into objective, morphologically interpretable biomarkers. We introduce a graph-based skeletonization of fat infiltrates to quantify muscle architectural changes, establishing a multi-dimensional extension of traditional, spatially-agnostic volume metrics by mapping topological networks across the entire 3D muscle volume. Statistical screening via non-parametric Kruskal-Wallis analysis confirmed the discriminative power of these novel descriptors across the genetic hierarchy. Notably, topological network metrics (e.g., SF1_Skel_Nodes, $\epsilon^2$ = 0.2656) and interface dynamics metrics (e.g., SF2_To_SF1_Dist_Min, $\epsilon^2$ = 0.2092) demonstrated substantial effect sizes, providing deeper structural insights than classical volumetric assessments. Post-hoc pairwise evaluations and UMAP projections further indicated the capability of these topological and 3D geometric invariants to capture disease-specific macroscopic infiltration patterns. These results demonstrate that global architectural features represent a highly promising class of biomarkers for differential diagnosis, offering new avenues for tracking longitudinal disease dynamics in neuromuscular diagnostics. The developed automated feature extraction pipeline is integrated and available within the MUSCAT (MUSCle fAt Topology) library.
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URL
https://arxiv.org/abs/2608.24415
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Markerless Pose Estimation for Resistance Training Technique Assessment
2026-08-25 10:44:05Joseph Turner, Jeff Clark, Nawid KeshtmandAbstract
Resistance training can be a high risk activity, and safe form is essential to avoiding injury. Laboratory-based movement analysis provides quantitive technique assessment, yet is not easily accessible. Markerless pose estimation infers body landmarks from images or video without physical markers and could offer a feasible alternative for technique assessment. We present a pose estimation framework to evaluate resistance-training technique from ordinary video footage. Using BlazePose, anatomical landmarks were extracted from squat, bench press, and deadlift videos and converted into joint-angle trajectories, with the squat serving as the primary case study. Trajectories were assessed against a defined reference repetition using root mean square error (RMSE). Results show that the framework recovers meaningful kinematic patterns for the squat and deadlift, enabling quantitative comparison between repetitions and identification of technique variability within a set. Performance depended strongly on camera orientation and visual occlusion, with non-sagittal views distorting 2D joint-angle estimates. The findings demonstrate that markerless pose estimation can support accessible biomechanical assessment outside laboratory environments.
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URL
https://arxiv.org/abs/2608.24384
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Keep-or-Drop? Adaptive Tokenizer for Compact Video Representation
2026-08-25 09:19:22Yeonkyeong Lee, Hyunsung Go, Jongmin Kim, Sewoong Lim, Donghoon LeeAbstract
Latent diffusion models have emerged as a dominant framework for high-fidelity image and video synthesis, operating in compact latent spaces with variational autoencoders (VAEs) to enhance computational efficiency without compromising visual quality. However, conventional VAEs are suboptimal for video data as they employ fixed compression ratios that cannot adapt to the varying complexity of spatio-temporal content. We present KATok (Keep-or-Drop? Adaptive Tokenizer for Compact Video Representation), a transformer-based VAE that incorporates an adaptive token selector which is jointly learned with latent tokens. By evaluating each token's content-richness as keep-or-drop probability, the token selector effectively discards uninformative tokens, naturally allowing data-dependent compression. Applying adaptive tokenization to diffusion models may cause spatial misalignment, as token dropping can disturb the original spatio-temporal structure. To alleviate this issue, we propose two position-prediction strategies: cascaded and joint generation, to ensure spatial consistency. We empirically show that our model achieves strong reconstruction and generation quality at a state-of-the-art compression ratio. Further analysis on video data reveals that this improvement is primarily achieved by reducing spatio-temporal redundancy and removing uninformative tokens, as supported by both quantitative and qualitative results.
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URL
https://arxiv.org/abs/2608.24293
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Eating for a Sustainable Planet: Personalized Sustainable Diet Recommendation via Constraint-Aware Decision-Making Modeling
2026-08-25 09:01:19Ying Jin, Weiqing Min, Mingyu Huang, Shuqiang JiangAbstract
A sustainable diet represents a multi-dimensional synergy among four essential pillars: nutrition adequacy, economic affordability, cultural acceptability, and environmental respect. Despite the prevalence of population-level sustainability modeling, practical implementation relies on effective individual-level adoption. This transition is often hindered by inter-individual heterogeneity, posing a formidable challenge in aligning sustainable diet requirements with individual preferences. To address this issue, we propose a personalized sustainable diet recommendation model based on a constraint-aware decision-making mechanism, where sustainability is incorporated through learnable constraints rather than modeled as user preferences. To systematically evaluate the proposed approach, we construct a sustainable diet dataset named SusDiet with about 150k recipes, characterized by broad coverage of sustainability indicators. Experimental results on this dataset show that our method promotes more sustainable choices without compromising individual preference. This work establishes a framework for aligning individual dietary choices with planetary health, offering quantitative evidence to guide future sustainable diet interventions and policy-making for sustainable development.
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URL
https://arxiv.org/abs/2608.24274
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LUCAID: Agentic Multimodal AI for Lung Cancer Precision Pathology
2026-08-24 20:07:04Marie-Lisa Eich, Kai Standvoss, Timo Milbich, Alexander M\"ollers, Miriam H\"agele, Philipp Anders, Lars Tharun, Hanna Kontradiuk, Sebastian Kons, Nader Aldoj, Recepcan Adig\"uzel, Adam Narai, Lukas H\"onig, Jonathan Striebel, Binru Yang, Mihnea P. Dragomir, Marvin Sextro, Philipp Keyl, Philipp Jurmeister, Rosemarie Krupar, Evelyn Ramberger, James Wells, Julika Ribbat-Idel, Andreas Kunft, Hussam Shuaib, Christian Groh\'e, Reinhard B\"uttner, David Horst, Klaus-Robert M\"uller, Lukas Ruff, Maximilian Alber, Frederick Klauschen, Simon SchallenbergAbstract
Lung cancer tissue diagnostics is complex, as therapy decisions in precision oncology rely on the integration of histomorphological, immunohistochemical, and molecular features. Yet pathological assessment remains largely visual and semi-quantitative and shows interobserver variability, while existing artificial intelligence (AI) tools cover only selected tasks, rarely reach generalizable expert-level performance, and lack prospective clinical validation. To address these challenges, we developed and clinically validated LUCAID, an agentic AI system for precision lung cancer pathology. An integrative agent couples diagnostic reasoning with nine modules that cover the full routine workflow, from quality control, tumor detection and segmentation, histological subtyping, tumor microenvironment profiling, tumor cellularity quantification, and predictive biomarker scoring (PD-L1, MET, TROP-2) to automated structured report generation. LUCAID enables users to interactively query the module outputs and generate reports that contextualize the results. Against large-scale expert ground-truth annotations, the analysis modules achieved F1 scores of 0.82-0.95. In prospective clinical validation, LUCAID reached 93.0% concordance with an expert-panel adjudicated reference standard across clinically actionable decisions, compared with 68.3-81.1% for five experienced thoracic pathologists.
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URL
https://arxiv.org/abs/2608.23803
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A Comprehensive Analysis of Arabic Natural Language Processing Research: Trends, Topic Evolution, and Research Gaps -- A Bibliometric and Topic-Based Study
2026-08-24 16:02:15Mullosharaf K. ArabovAbstract
Natural Language Processing (NLP) has grown rapidly over the past decade, driven by digital transformation in the Arab world, social media, and large language models (LLMs). Despite this growth, a comprehensive quantitative meta-analysis of the field remains absent. This study presents a large-scale bibliometric and topic-based analysis of 7,120 Arabic NLP papers published between 1960 and 2026, sourced from six collections. We employ BERTopic for topic modeling, regression analysis to identify citation predictors, social network analysis for co-authorship structures, and geographic mapping. Our findings show a significant publication surge after 2020, driven by transformer models and LLMs. Topic modeling identifies 19 substantive themes, the largest centered on text, speech, translation, and recognition. Citation analysis reveals a positive correlation between paper age and citations (r = 0.245, p < 0.001); regression shows that indexing in OpenAlex or Semantic Scholar and institutional affiliation are associated with higher citation counts. Saudi Arabia, the United States, and Egypt lead in research output. A task-dialect gap matrix identifies critical understudied areas, including summarization for Maghrebi, Iraqi, and Sudanese dialects. The largest topic has the highest H-index (87), followed by sentiment analysis (54). Our quantitative approach complements existing qualitative surveys and offers recommendations to prioritize under-resourced dialects and develop culturally aligned benchmarks for Arabic NLP.
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URL
https://arxiv.org/abs/2608.23421
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