Modern deep learning models achieve impressive generalization through over-parameterization, but this paradigm often struggles with overfitting and memorization in few-shot regimes. Neural Cellular Automata (NCAs) offer a highly parameter-efficient alternative, yet research has focused primarily on their output, leaving the role of their internal hidden channels largely unexplored. In this paper, we investigate the internal dynamics of NCA hidden channels and introduce a novel transfer-learning mechanism that injects a pretrained teacher's hidden states into a student model to guide early optimization. Evaluated on few-shot and scale-variant MNIST benchmarks, NCAs outperform comparable recurrent and feed-forward architectures, demonstrating superior generalization with a minimal parameter budget (~9,800 parameters). Mechanistic analysis reveals that the hidden channels decouple feature extraction from uniform classification consensus by absorbing morphological complexity and converging to mutually orthogonal states. Furthermore, we demonstrate that these hidden channels capture general, scale-invariant topological primitives rather than class-specific templates. This allows a student model to achieve strong few-shot performance on unseen classes using features transferred from a teacher trained only on a subset of digits (0-5). Our results highlight the potential of utilizing hidden-state dynamics as a robust, decentralized computational substrate for parameter-efficient transfer learning
https://arxiv.org/abs/2609.21870
Deep learning-based visual odometry (VO) has achieved significant progress, yet most existing methods focus on a monocular approach, which suffers from scale ambiguity. Stereo VO provides real metric by its nature, but remains less studied in deep learning VO due to its high computational cost and modeling complexity. Recent advances in stereo matching and optical flow estimation have made dense visual correspondence increasingly accurate and reliable, but their complementary geometric information has not been fully exploited for VO. In this paper, we present SFVO, a correspondence-driven stereo VO framework that directly builds upon pretrained stereo matching and optical flow models. SFVO exploits pretrained stereo matching and optical flow models to estimate stereo and temporal correspondences. Instead of learning pose directly from images, SFVO maps learned correspondences into geometric constraints and predicts which points are trustworthy. To improve the reliability of visual correspondence-based geometric constraints, we introduce decoupled confidence maps for rotation and translation. This design better aligns the characteristics of visual correspondence and 6-DoF transformations. Extensive experiments on outdoor and indoor datasets demonstrate that SFVO achieves robust and accurate pose estimation with strong generalization capability. The code will be released.
https://arxiv.org/abs/2609.21754
Deep learning segmentation of renal tumors requires large annotated datasets, yet clinical deployments typically offer only a handful of tumor-positive cases from the target site. We propose a diffusion-based inpainting framework that synthesizes anatomically plausible renal tumors within healthy CT scans, requiring no additional annotation, and provide the first systematic comparison of 2D, 2.5D, and full 3D (MAISI) synthesis strategies for this task. Training the diffusion model on public data (KiTS23, KIRC) and evaluating nnU-Net segmentation on a internal cohort across three low-data regimes, we find that 2.5D and 3D augmentation substantially reduce false positives (from $\sim$18--20\% to $\sim$3--6\%) while maintaining Dice, whereas 2D provides no consistent benefit. Crucially, the proposed 2.5D method matches full 3D synthesis on every metric at substantially lower computational cost, indicating that local volumetric consistency alone is sufficient for effective augmentation in data- and resource-scarce clinical settings.
https://arxiv.org/abs/2609.21698
Automated electrocardiogram diagnosis using deep learning remains limited by signal-agnostic representations that treat multi-lead recordings as undifferentiated time-series or images, forcing models to rediscover physiological structure implicitly. This leads to data inefficiency, poor generalization, and opaque decision boundaries misaligned with clinical reasoning. We present BEAT-Net, a supervised biomimetic framework that integrates QRS-centered biological tokenization with a hierarchical architecture mirroring the cardiologist's workflow. A QRS tokenizer converts continuous signals into semantically complete heartbeat sequences, which are processed through four specialized stages: morphological feature extraction via a Word Encoder, lead-invariant normalization through a Spatial Operator, temporal context injection by a Temporal Operator, and global reasoning using a Transformer-based Sentence Encoder. Evaluated across three large-scale benchmarks including PTB-XL, CPSC2018, and CSN, BEAT-Net achieves diagnostic accuracy of 0.924 AUC, comparable to dominant CNN baselines at 0.925 AUC, while reducing parameters by 95 percent from 2.06 million to 0.7 million. Critically, BEAT-Net surpasses the 39.5-million-parameter foundation model HeartLang on morphological Form classification, reaching 0.901 AUC compared to HeartLang's 0.832 AUC, while attaining full CNN-level performance using only 35 percent of training data and exhibiting superior cross-dataset generalization. Learned attention patterns spontaneously align with established clinical heuristics, demonstrating that explicit physiological structure provides a more efficient and interpretable alternative to massive pre-training for clinical deployment.
https://arxiv.org/abs/2601.07316
Producing accurate annotations for deep learning based image segmentation is both costly and labor intensive. This challenge is especially evident in wildland fire applications, where accurately labeled datasets are scarce due to the difficulty of collecting and annotating dynamic fire scenes. To address this problem, our previous work introduced the Centralized Copy-Paste Data Augmentation (CCPDA) method for semantic segmentation of wildland fire imagery, which generates artificial training samples by randomly pasting fire clusters from source images onto target images. However, random placement can produce contextually unrealistic scenes, such as fire burning on asphalt. In this paper, we present a context-aware strategy designed specifically to improve data quality and realism in small multiclass wildland fire datasets, ensuring that augmented samples remain contextually meaningful. The proposed method restricts fire placement to semantically valid target regions and selects the location whose Ash-Vegetation composition most closely matches the source context. This approach preserves existing fire regions in the target image, prevents unrealistic placements, and maintains contextual accuracy by generating images that resemble real wildland fire scenes. We evaluate the Context-Aware CCPDA strategy through numerical analysis and comparisons with other augmentation methods by a weighted sum-based multi-objective optimization (MOO) approach. The results confirm that the context-aware data augmentation strategy leads to improved segmentation performance and contextual realism, outperforming other augmentation procedures.
https://arxiv.org/abs/2609.21241
Automatic target recognition (ATR) with synthetic aperture sonar (SAS) supports advanced naval capabilities, but deep learning is constrained by scarce target imagery, background clutter, and human-in-the-loop assessment. We adapt DINOv3 Vision Transformer (ViT) models to underwater SAS ATR using a three-stage parameter-efficient framework. Stage 1 uses Low-Rank Adaptation (LoRA) while freezing the ViT backbone, bridging the gap between natural-image pretraining and underwater acoustic propagation. Stage 2 uses hard-negative mining to strengthen the decision boundary against acoustic mimics, including rocks and sediment formations resembling man-made targets. Stage 3 uses Supervised Contrastive Learning (SupCon) to separate target and clutter representations. We evaluate at-sea SAS data using a mission-level geographic split, compare all arms at 85 percent test recall, and repeat each comparison over three random seeds. LoRA accounts for the primary effect, increasing area under the precision-recall curve (AUPRC) from 0.300 to 0.679 +/- 0.027 using the same frozen backbone. Rank 4 achieves this result while training only 0.26 percent of weights. Neither refinement stage exceeds its matched control: hard-negative mining changes AUPRC by -0.0045 +/- 0.0119 versus an equal-size random curriculum, and SupCon changes AUPRC by +0.0002 +/- 0.0096 versus the preceding stage. These null results indicate that mining occurred on data the encoder had already fit and that supervised stages had already imposed most target-clutter geometry. One efficient adaptation stage is sufficient; stacked refinement is not.
https://arxiv.org/abs/2609.21061
In this work, we present an uncertainty-driven training framework for three-dimensional computed tomography (CT) lung nodule classification, where validation-based uncertainty estimates guide loss reweighting to enhance predictive performance and probability calibration. Two Uncertainty Quantification (UQ) methods are considered: Monte Carlo Dropout (MCD) and Evidential Deep Learning (EDL). Both provide per-class uncertainty estimates that modulate the loss and encourage focus on hard or unreliable classes. The framework is evaluated with ResNet, DenseNet, EfficientNet, Vision Transformer (ViT), and Swin Transformer backbones on two datasets: the clinical LIDC-IDRI cohort and the NoduleMNIST3D benchmark. Uncertainty-driven training achieves classification performance similar to conventional training while substantially improving calibration, with an expected calibration error (ECE) reduced by up to 65% on LIDC-IDRI. EDL attains competitive performance on shallower architectures with single-pass inference, whereas MCD is more robust on deeper networks. Analysis across architectural families reveals that uncertainty-driven training benefits convolutional backbones more consistently than transformer-based architectures: EDL in particular degrades on ViT, suggesting that the Dirichlet evidence parameterisation may interact unfavourably with attention-based architectures at lower input resolutions. A posteriori temperature scaling proves highly effective across all configurations, indicating that a simple scalar calibration can be competitive even without explicit uncertainty-aware training. Our results indicate that integrating UQ into the training loop can significantly improve probabilistic calibration and support more trustworthy deployment of three-dimensional medical imaging models.
https://arxiv.org/abs/2609.20905
Invoices are commercial documents that contain various pieces of information, including the purchased items, time, and total money. Making the extraction of important information crucial. The stored information serves different purposes. Korean language is the native language of about 80 million people, playing an important role in not only South and North Korea but also in many other countries such as Vietnam, Philippine where a large number of Korean companies are located. In this context, to automatically extract proper information from the invoices with Korean language, we propose an efficient Optical Character Recognition (OCR) model in which a deep learning model is combined with some image preprocessing techniques. The proposed OCR model is assessed in a rich set of collected invoices showing that 87% F1-score can be achieved with negligible time processing.
https://arxiv.org/abs/2609.35796
Deep learning predictive maintenance models suffer from poor transferability across machines and operating conditions, especially when labelled data are scarce and signals span five orders of magnitude in sampling frequency (1 Hz to ~100 kHz). We propose FreqCondNorm, a Transformer-based architecture that introduces a FiLM-style frequency-conditioned normalization layer to unify heterogeneous time-series within a single model. The architecture is pretrained on five public predictive maintenance datasets (CWRU, MFPT, UOC18, PRONOSTIA, CMAPSS) using masked auto-encoding and contrastive learning with balanced domain sampling. On fault diagnosis, the model achieves 99.2% accuracy on CWRU (+6.4 pp over CNN) and 82.1% zero-shot accuracy on MFPT, demonstrating strong transfer across sampling frequencies. However, the approach does not improve remaining useful life prediction, suggesting a mismatch between pretraining and RUL objectives that warrants future investigation.
https://arxiv.org/abs/2609.20535
The categorization of cognitive and resting states derived from electroencephalography (EEG) signals is crucial for comprehending fluctuations in brain activity linked to various mental states. EEG provides a non-intrusive approach for documenting brain function in both resting and task-oriented cognitive conditions, whilst deep learning techniques enable the automatic extraction of significant patterns from intricate EEG data. This study presents a deep learning framework to distinguish between resting and cognitive states through EEG records. The proposed framework integrates a Convolutional Neural Network (CNN) stacked with a Gated Recurrent Unit (GRU) for the extraction of features from EEG signals. Time-frequency analysis is conducted to explore the salient aspects of signals, and the derived features are then assessed utilizing conventional deep learning and machine learning classifiers, including the suggested 2D-Net architecture. The proposed approach and feature extraction strategy outperform the evaluated comparative methods, achieving accuracies of 83.177% for resting-versus-mathematical task classification, 76.107% for resting-versus-memory task classification, and 83.432% for resting-versus-music task classification. The findings illustrate the efficacy of integrating signal processing with deep learning methodologies to discriminate resting from cognitive states utilizing EEG signals.
https://arxiv.org/abs/2609.20467
Objectives: Quantitative assessment of infarct hypodensity on non-contrast computed tomography (NCCT), including net water uptake (NWU), requires manual or semi-manual lesion delineation, often guided by CT perfusion or diffusion-weighted MRI, limiting clinical applicability. Automated segmentation on NCCT could enable efficient biomarker extraction such as NWU but remains challenging across heterogeneous multicenter data. This study aimed to develop and externally test a domain-aware deep learning framework for ischemic stroke segmentation on NCCT and assess its suitability for NWU quantification. Materials & Methods: In this retrospective multicenter study of 801 patients from four datasets, an nnU-Net-based model was trained on NCCT scans from the University Medical Center Hamburg-Eppendorf and the Acute Ischemic Stroke Dataset. To adapt to new domains, the model was fine-tuned on target-domain subsets from Boston (n=11) and ISLES (n=75), with evaluation on held-out cases not used for fine-tuning. Automated segmentations and NWU values were compared with expert references. Results: For lesions $\geq$ 30 mL, median Dice was 0.68 (Boston) and 0.56 (ISLES). Including smaller lesions, which predominated in ISLES, median Dice was 0.54 (interquartile range [IQR] 0.30-0.70) for acute lesion segmentation (Boston dataset) and 0.20 (IQR 0.03-0.41) for NCCT lesion segmentations when compared to post-treatment infarct (primary target of the ISLES challenge). Automated NWU mean absolute error was 1.37 percentage points (SD 1.61, Boston). Conclusion: Target-domain adaptation supported NCCT-only infarct segmentation across heterogeneous external cohorts, although performance varied across domains. The approach enabled low-error NWU quantification from baseline NCCT without advanced imaging, supporting further prospective clinical evaluation.
https://arxiv.org/abs/2609.20151
Deep learning models for multi-modal breast cancer diagnosis achieve high predictive accuracy but remain clinically unacceptable without actionable, counterfactual explanations. Attribution-based methods (LIME, SHAP) are categorically inapplicable to this purpose, as they generate no alternative instances and thus cannot be evaluated on counterfactual quality metrics. This investigation provides empirical evidence that FCA-Guided Counterfactual (FCA-CF) framework that uses a Formal Concept Analysis (FCA) concept lattice as a hard structural constraint on counterfactual search, operating over a multi-modal TCGA-BRCA dataset. We benchmark against four genuine counterfactual methods: Wachter-style CF, DiCE, FACE, and NICE, evaluated on 60 benign-predicted TCGA-BRCA instances. The FCA-CF framework achieves Validity = 1.0000 (100% of counterfactuals successfully flip the prediction), Sparsity = 2.37 features changed (best among all valid methods), and Proximity = 0.900 (normalised L2-based, matching NICE as joint best). The classifier achieves Accuracy = 0.980, F1 = 0.976, ROC-AUC = 0.9947. Ablation analysis confirms that the FCA lattice constraint is the primary sparsity driver (removing it increases sparsity by +40%, p < 0.001, Cohen's d = 0.78), while Phase C greedy refinement accounts for the largest individual contribution (+113% sparsity increase when disabled, p < 0.001, d = 5.01). FCA-guided counterfactual generation achieves a clinically important Pareto-dominant outcome; it is simultaneously the sparsest and among the most proximate of all valid methods, with perfect validity. The emergent sparsity property arising from lattice topology rather than numerical penalty terms constitutes a structurally novel contribution to the counterfactual explanation literature.
https://arxiv.org/abs/2609.20067
Time series forecasting has seen signicant advancements with the emergence of new deep learning models. However, forecasting time series in applications involving physical processes remains a major challenge. Despite the apparition of Physics Informed Neural Networks (PINN), recent models do not estimate unobservable intermediate physical variables, which are important for domain experts to understand the target behavior. To this end, we propose a Physics Informed Recurrent Neural Network (PIRNN) which predicts, along the target, unobservable variables on both historic data and forecast target. This approach enhances the model robustness and results interpretation using domain knowledge. Our method is easily adaptable to any physical model using several equations, each having its own set of unobservable variables, to describe it-self. As a case study, we incorporate physical equations used for groundwater levels predictions by the physical model called Gardenia. This model uses transfers equations between reservoirs, optimized with data assimilation, to simulate the evolution of groundwater levels. Evaluation includes several well known neural network models and the Gardenia model compared on twelve real world datasets. In addition, we study the impact of each component through an ablation study. Our model outperforms other models on ve out of the twelve datasets and our ablation study underlines the importance of having a physical background in our time series forecasting task. Finally, the coherence of the physical variables predicted by our neural network is assessed by a domain expert.
https://arxiv.org/abs/2609.19871
Accurate classification of brain disorders from neuroimaging data remains challenging because of substantial inter-subject heterogeneity and the complex multi-scale patterns present in functional connectivity and morphological representations. To address these challenges, we propose HyperAMS-Net, a deep learning framework for brain disorder classification using neuroimaging representations derived from resting-state functional MRI or structural MRI. HyperAMS-Net integrates adaptive multi-scale convolution, hypergraph attention, spatial-channel attention, and adaptive feature fusion. Specifically, adaptive multi-scale convolution learns data-driven weights over multiple receptive fields to capture complementary patterns at different scales. Hypergraph attention models higher-order dependencies among learned feature representations through node--hyperedge--node message passing, while spatial-channel attention enhances discriminative feature learning. Adaptive feature fusion further aggregates complementary information across parallel network branches. HyperAMS-Net is evaluated on three benchmark datasets spanning distinct brain disorders: ABIDE for autism spectrum disorder, REST-meta-MDD for major depressive disorder, and ADNI for Alzheimer's disease, using 5-fold stratified cross-validation. HyperAMS-Net achieves state-of-the-art performance across all evaluated datasets, attaining the highest accuracy and AUC among the compared methods. Ablation studies further demonstrate the contribution of each proposed component, with the largest performance degradation observed when hypergraph attention is removed.
https://arxiv.org/abs/2609.19755
Recent innovations in deep learning have significantly enhanced the diagnosis of medical images, although they are based on the use of centralized data storage that pose severe threats to patient privacy and medical data security. To address this issue, this research proposes a Federated Learning (FL) model that is coupled with an optimized YOLOv8 network to detect the kidney stones on a computed tomography (CT) image and at the same time, protect privacy of the patients. The suggested system can help various medical organizations to jointly train a common model without exchanging the information about the patients. This is to ensure that data protection laws like GDPR and HIPAA are adhered to. The residual feature fusion and DropBlock regularization among other architectural improvements are also included in YOLOv8 to enhance detection robustness and minimize overfitting. Experimental analysis carried out on a distributed CT dataset demonstrated that the federated YOLOv8 model has a mAP at 50 of 0.733 and is able to keep the data confidential. Moreover, its lean design facilitates fast edge deployment and real-time inference across a clinical setting. Altogether, these findings indicate that Federated Learning is a safe and efficient solution to AI-assisted diagnosis in contemporary healthcare when combined with the use of sophisticated object detection models.
https://arxiv.org/abs/2609.19740
Accurate estimation of left ventricular ejection fraction (EF) from echocardiography is central to cardiovascular care, and deep learning enables automated EF prediction from echocardiographic video. Because EF is clinically derived from left-ventricular (LV) volumes, a widely held intuition is that explicit LV segmentation should improve prediction. We introduce a quantitative criterion, the segmentation ceiling, that makes this testable: from EF as a normalized difference of end-diastolic and end-systolic volumes, we derive in closed form how per-frame segmentation area error propagates into EF error, and thus the accuracy a mask must reach before it can improve on direct regression. Using EchoNet-Dynamic, a UniFormer-S backbone, and the empirically measured within-patient error correlation, the criterion places the break-even near 10% per-frame area error, whereas a representative segmenter operates at roughly 14%, above the ceiling. Consistent with this, four strategies for injecting segmentation or area information (a predicted-mask channel, end-diastolic/end-systolic clip sampling, and per-bin and amplitude area-consistency objectives) fail to beat a raw-video baseline; ground-truth masks help only through label leakage. Input representation thus not being the limit, we identify generalization as the practical lever: weight averaging with strong augmentation attains a test R^2 of 0.806 (MAE 4.08) under a matched dense-clip protocol, comparable to an R(2+1)D baseline (0.811) while tightening the validation-to-test gap. Finally, a heteroscedastic beta-NLL formulation yields informative, well-calibrated per-prediction uncertainty, larger for clinically harder low-EF cases, where Monte-Carlo dropout does not. The segmentation ceiling gives a concrete design criterion for when mask-guided EF estimation is worthwhile, plus a simple, uncertainty-aware recipe for EF regression.
https://arxiv.org/abs/2609.19730
This study developed and evaluated a deep-learning-based perception framework for selective robotic cotton picking. The dataset contained 1,008 annotated field images collected using three cameras under varying natural lighting and weather conditions. Object-detection models from the YOLOv8 through YOLOv13 families were evaluated using their default configurations, while segmentation performance was assessed using YOLOv8-seg, YOLOv11-seg, YOLOv12-seg, the Segment Anything Model (SAM), SAMv2.1, FastSAM, and Grounded-SAM with the Recognize Anything Model (RAM). Among the detection models, GELAN-s achieved the most favorable balance between mean average precision (mAP) and inference speed, obtaining an mAP of 86.1%, precision of 81.6%, recall of 76.6%, and an F1-score of 79.0%, with an average inference time of 42.3 ms per image. Among the direct segmentation models, YOLOv12-m-seg provided the most favorable balance between AP@0.5 and FPS, achieving a segmentation AP@0.5 of 83.7% with an inference time of 20.4 ms per image. In the detection-prompted segmentation approach, bounding-box prompts generated by GELAN-s improved the localization of cotton bolls for SAM and SAMv2.1, while SAMv2.1 Tiny consistently outperformed FastSAM and Grounded-SAM with RAM. In the area-based evaluation against manually annotated segmentation masks, YOLOv12-m-seg achieved an $R^2$ value of 0.966, compared with 0.860 for GELAN-s + SAMv2.1 Tiny. Field experiments conducted using a UR5e robotic manipulator, a custom end-effector, and a ZED2i stereo camera further validated the effectiveness of the YOLOv12-m-seg model for real-time cotton boll detection, segmentation, and selective picking under varying confidence levels. These results demonstrate that YOLOv12-m-seg provides an efficient perception model for robotic cotton harvesting and has strong potential for field deployment.
https://arxiv.org/abs/2609.19592
Scaling deep learning faces critical bottlenecks: data exhaustion, exponential training costs, and resource concentration. Model merging combines pre-trained checkpoints without gradient descent, offering orders-of-magnitude savings versus retraining. Combining independently trained vision models is difficult when their architectures and parameter shapes differ. Existing weight-space merging methods generally assume aligned, shape-compatible checkpoints, whereas a Vision Transformer (ViT) and a state-space model (SSM) implement token mixing with different operators. We study a hybrid Heterogeneous merging setting that retains both architectures while aligning parameter groups by semantic role. Our proposed Riemannian--Lorentz Parameter Fusion (RLPF) method projects aligned groups to common coordinates, lifts selected coordinates to the Lorentz hyperboloid model of hyperbolic space, computes a regularized geodesic barycenter, and decodes the result into the two branches. A learned gate then combines branch logits for each input. Component groups use fixed curvature values, with normalization parameters treated as Euclidean. In the results available in this manuscript, the fine-tuned system obtains 82.37\% on CIFAR-10, 75.04\% on Oxford-IIIT Pet, and 78.58\% top-1 accuracy on ImageNet-1K; the corresponding best-parent accuracies are 76.54\%, 71.42\%, and 76.42\%. On ImageNet-1K, the reported pre-fine-tuning initialization reaches 77.80\%. These results support further study of geometry-aware heterogeneous fusion, but not a training-free single-checkpoint merge: RLPF is a two-branch hybrid whose gate and reported final models are trained.
https://arxiv.org/abs/2609.19384
Clinical decision-making for coronary intervention relies mainly on angiography and fractional flow reserve (FFR). However, angiography is two-dimensional and lacks depth information for 3D lesion characterization, while FFR provides only a single functional index, offering limited hemodynamic insight. Among existing methods, numerical analysis is computationally expensive, whereas learning-based approaches require extensive supervision and often lack physical consistency. To address these limitations, we propose physics-informed hemodynamic modeling, an integrated deep learning framework for 3D coronary blood flow analysis from dual-view angiography. First, an attention-enhanced CNN reconstructs coronary geometry from angiography. The resulting point clouds are then mapped to a reference domain and Fourier-encoded for joint representation. A decoupled network separately predicts velocity and pressure fields, with embedded physical priors enabling efficient transfer across physiological conditions. Across 32 clinical patients evaluated under four flow conditions, the trans-stenotic pressure-drop mean absolute percentage error was 2.02%, while the velocity and pressure relative-L2 errors were 0.054 and 0.023, respectively. Validation against hospital-measured FFR further achieved 93.8% diagnostic accuracy (30/32; exact 95% CI, 79.2%-99.2%). The framework also supports illustrative revascularization comparisons and sparse-data assimilation, with the full angiography-to-hemodynamics pipeline completed within 20 minutes per patient.
https://arxiv.org/abs/2609.19290
Long-range infrared imaging frequently confronts dense target clusters whose diffraction-limited signatures merge into a single indistinguishable blob, concealing the number, sub-pixel positions, and radiant intensities of the underlying sources. While deep learning has advanced general object detection, resolving such Closely-Spaced Infrared Small Targets (CSIST) remains largely unexplored, owing to a systemic infrastructure void and a fundamental paradigm mismatch. The dominant formulation, which reduces unmixing to a blind, discrete sub-pixel separation, is inherently insufficient: without semantic guidance, the ill-posed inverse problem admits ambiguous solutions plagued by false and missed detections, while grid-based discretization locks predictions onto fixed lattice centers, chaining precision to prohibitively expensive grid refinement. We argue that CSIST unmixing should instead be informed and continuous. To ground this paradigm shift, we establish the first comprehensive open-source ecosystem for the field, comprising the large-scale CSIST-100K benchmark, a tailored metric suite, and the GrokCSO toolkit. Upon this foundation, we propose DISTA-Net++, which anchors a dynamic deep unfolding backbone with two synergistic mechanisms: a Count-Guided Prior that injects the global target count as an explicit semantic constraint to regularize the solution space, and a Continuous Coordinate Rectification that regresses off-grid offsets to decouple localization accuracy from grid resolution. Extensive experiments validate our paradigm: even under the most economical 3x division, DISTA-Net++ surpasses 7x-division state-of-the-art methods by 16.15% in CSO-mAP and 62.96% in count accuracy at merely one-sixth of their computation, demonstrating that unmixing precision need not be purchased with finer discretization. The complete ecosystem is available at this https URL.
https://arxiv.org/abs/2609.18773