Abstract
Reconstructing cortical WM and pial surfaces from structural magnetic resonance imaging (MRI) is a prerequisite for surface-based neuroanatomical analysis, yet remains challenging because the cortex is thin and tightly folded. Reconstruction methods can produce geometric artifacts such as mesh self-intersections and collisions between cortical surfaces, and although recent deep learning methods have reduced reconstruction time from hours to minutes, these artifacts persist. We propose SimCortex v2, a deep learning framework for simultaneous reconstruction of the left and right WM and pial surfaces from T1-weighted MRI. SimCortex v2 estimates topologically correct initial surfaces from a volumetric segmentation and refines all four jointly using multi-scale stationary velocity fields predicted by a ribbon-conditioned, U-Net-like network. We evaluated SimCortex v2 on 560 cases from 14 cohorts, thirteen of them unseen during training, spanning ages 6-89, healthy and clinical populations, and scanners from three vendors. SimCortex v2 matched the surface-distance accuracy of the strongest baseline (average symmetric surface distance 0.253 mm) while showing no detected inter-surface collision in 92.14% of cases and the lowest self-intersection fraction (0.044%) among learning-based methods, whereas every baseline produced at least one collision in every case. Source code, configuration files, pretrained weights, preprocessed data, and the exact evaluation splits are publicly released.
Abstract (translated)
URL
https://arxiv.org/abs/2610.07378
