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De-GAN - Dynamic Parameter Tuned GAN for 3D Medical Image Segmentation: A Step Towards Generalisation

2026-09-15 07:32:48
Zoha Usama, Azadeh Alavi
arXiv_CV
           
Abstract

Brain tumor segmentation remains difficult because enhancing tumor (ET) has low contrast and overlaps surrounding tissue, while scanner and site variation causes domain shift. We propose DE-GAN, a contrast-enhancing conditional GAN that combines input-adaptive dynamic convolutions, style-aware feature mixing, and coordinate encoding to synthesize slice-adaptive FLAIR images. A label-guided, class-conditional target separates tumor-core (TC) and ET intensities while preserving anatomy. The generated FLAIR is concatenated with the original MR modalities and used to train a 3D U-Net. Across BraTS 2015, 2018, and 2019, DE-GAN improves segmentation over the baseline and static EnhGAN replacement on most reported TC/ET metrics, with the largest gains from retaining both original and enhanced FLAIR. Code and pretrained models are available at this https URL.

Abstract (translated)

URL

https://arxiv.org/abs/2609.16755

PDF

https://arxiv.org/pdf/2609.16755.pdf

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