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AMPLIFAI: A Multiphase CT Dataset for Benchmarking Clinical Reasoning in LI-RADS Assessment of Liver Lesions

2026-08-14 17:59:54
Pranav Kulkarni, Nikhil Shah, Amritansh Suryavanshi, Jana Delfino, James Tonascia, Jade Wong-You-Cheong, Barton Lane, Joseph Chirico, Jeffrey D. Hirsch, Ang Li, Heng Huang, Florence X. Doo

Abstract

Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related mortality worldwide, with early detection improving survival from <20\% to >70\%. The standardized LI-RADS criteria establish a biopsy-free, fully imaging-based framework that can serve as a foundation for automating HCC diagnosis with artificial intelligence (AI). However, the lack of large, publicly available datasets with high-quality labels has limited the development of AI models for LI-RADS characterization. We introduce the \textbf{AMPLIFAI} dataset, the first public dataset of multiphase abdominal CT scans annotated with LI-RADS categories and segmented for three major LI-RADS features: arterial phase hyperenhancement, washout, and enhancing capsule. Following the \emph{Datasheets for Datasets} format, this paper details the dataset's composition, curation process, and annotation pipeline to facilitate transparent, reproducible research.

Abstract (translated)

URL

https://arxiv.org/abs/2608.14778

PDF

https://arxiv.org/pdf/2608.14778.pdf


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