Medical
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ThuRunel: Dynamic Decoupling for Structured Advisory Dialogue
2026-09-28 22:23:43Yuyan ChenAbstract
High-stakes advisory domains such as medical aesthetics, legal consultation, and educational planning exhibit a two-phase structure. The early phase requires empathetic elicitation and emotional support, and the late phase requires authoritative specialist judgment. Neither fully automated agents nor human junior consultants adequately address this structure at scale. We formalize the core design challenge as dynamic decoupling, asking how an AI advisory agent should decide what to ask, when to stop, what to resolve autonomously, and what to forward to the specialist. We present ThuRunel, an advisory agent combining a finite-state belief management framework, a chain-of-thought teacher synthesis protocol, and learned generation adapters. Against eleven baselines, ThuRunel achieves consistent improvements in elicitation completeness and specialist brief quality. ThuRunel is publicly deployed as a bilingual web application in which the same decoupling decisions operate from the client's side, grounded in a curated knowledge base that cites its sources in every answer.
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URL
https://arxiv.org/abs/2609.36340
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FD-AA: A Lightweight Focal-Diffuse And Attenuation-Aware Head for Incidental Abdominal Abnormality Detection in Chest CT
2026-09-28 19:54:19Haoyan Ding, Kritika Iyer, Halid Yerebakan, Zhenyu Bu, Chushu Shen, Peiyu Duan, Xinyuan Zheng, Sepehr Farhand, Xueqi Guo, Chaowei Wu, Yoshihisa Shinagawa, Gerardo Hermosillo ValadezAbstract
Routine chest CT captures upper-abdominal structures that may contain clinically relevant incidental abnormalities. Detecting these findings requires feature extraction from organs with different spatial extents and attenuation patterns. We propose FD-AA, a lightweight organ-aware classification head adaptable for frozen 3-D CT encoders. Within each organ, an attenuation-aware module preserves sparse focal evidence, while masked generalized-mean pooling captures diffuse anomaly patterns. In seven abdominal organs, FD-AA with Pillar-0 achieved state-of-the-art (SOTA) performance in both the CT-RATE test set (AUC = 0.798) and the external RAD-ChestCT dataset (AUC = 0.713). More specifically, FD-AA improved macro AUC/AP from 0.763/0.346 to 0.798/0.405 over direct classification using frozen Pillar-0 only (p = 0.034/0.016). Such performance gain generalizes across multiple frozen encoders (AUC improvement on MedicalNet +9.8%, CT-CLIP +14.7%, ResNet +3.7%), demonstrating the effectiveness of FD-AA across different feature representations. These results support the effectiveness of integrating focal-diffuse aggregation with explicit HU evidence for incidental abdominal abnormality detection.
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URL
https://arxiv.org/abs/2609.36189
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Exploring Learning Models for Topological Relationship Recognition from Image Data
2026-09-28 19:42:06Saptak Das, Monidipa DasAbstract
Figuring out how objects relate to each other, like whether they touch, overlap, stay completely separate or one sits inside another, matters a lot in fields like GIS, biomedical imaging, and robotics. Even though machine learning has come a long way, people haven't really focused on spotting these topological relationships in images. The main roadblocks? Not enough good datasets and no clear way to measure results. So, we rolled up our sleeves and built a new dataset. It's pretty sizable: over 11,000 labelled images showing all those essential relationships. We ran tests with some classic machine learning models, Naive Bayes, KNN, Random Forest, SVM, and Artificial Neural Networks, and threw in some deep learning stars like VGG16 and InceptionResNetV2. For the dataset itself, we used segmentation, contour detection, and grayscale normalization to tease out solid feature vectors. The results? Deep learning methods, especially VGG16, pulled ahead, with validation accuracy hitting 89.55%. That's a big jump compared to the traditional models. This shows how powerful transfer learning is for analyzing topological relationships in images, and it gives researchers a new standard to aim for in future work on spatial reasoning and topological classification.
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URL
https://arxiv.org/abs/2609.36172
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Hardware-Aware Functional Kolmogorov-Arnold Networks for Efficient Medical Image Enhancement and Segmentation
2026-09-28 19:08:15Mohammad Sadegh SirjaniAbstract
Functional Kolmogorov-Arnold Networks (FunKAN) achieve state-of-the-art accuracy on MRI Gibbs artifact removal and anatomical segmentation, but their 11.6 M parameters and 8.7 GFLOPs are too large for edge medical devices. We present FunKANLite, a two-stage, hardware-aware compression of FunKAN for point-of-care use. FunKANLite-TR reduces the spatial prior and replaces the ResBlock offset predictor with a depthwise-separable block. It has 1.9x fewer parameters than FunKAN and no loss in accuracy. We then distill FunKANLite-TR into FunKANLite-ST, which lowers the Hermite basis rank, factorizes the spatial prior into a low-rank form, and halves the filter widths. FunKANLite-ST has 5.6x fewer parameters and 3.7x fewer GFLOPs than FunKAN. It stays within 1.4 percentage points IoU of FunKAN on BUSI, GlaS, and CVC-ClinicDB, and reaches 33.95 dB PSNR on IXI. On an NVIDIA Jetson Orin Nano and a Raspberry Pi 5, FunKANLite-ST reduces energy per inference by up to 68% and raises throughput by 2.9x.
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URL
https://arxiv.org/abs/2609.36134
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Medical Image Alignment Assessment as a Test of Generalist Visual Reasoning in Frontier Multimodal Models
2026-09-28 17:17:27Ross Callaghan, Niannu Gao, Hojjat Azadbakht, Hui ZhangAbstract
Frontier multimodal large language models (MLLMs) are increasingly positioned as general purpose visual reasoners as part of the quest for artificial general intelligence. A key test of this generality is whether they can perform novel visual judgments that humans can make reliably from visual evidence and task instructions, without task-specific parameter optimisation. We investigate this question through the task of medical image alignment assessment, where the goal is to establish whether there is anatomical correspondence between two images. Human visual assessment of image alignment is still the gold standard and most common approach; however, it requires trained operators and is impractical to scale for large datasets. We evaluate recent generations of MLLMs on two exemplar medical image alignment tasks, varying both prompting strategies and image-presentation methods. We compare against a locally fine-tuned MLLM and a task-specific CNN to examine the trade-off between frontier general purpose models and smaller models that require specific task optimisation but can be used locally. We show that are reaching an inflection point, where frontier MLLMs can now perform effective visual assessment of medical image alignment. Models released only a few months ago generalise poorly and, in some settings, perform barely above chance, whereas GPT-6 achieves over 85% across almost all scenarios tested. Fine-tuned local models can match or exceed frontier-model performance on the tasks on which they are trained, but transfer substantially less effectively to unseen settings. These findings identify medical image alignment as a useful test bed for generalist visual reasoning and suggest that frontier multimodal models are beginning to acquire capabilities that could support a common quality-control mechanism across heterogeneous medical-imaging pipelines.
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URL
https://arxiv.org/abs/2610.06896
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Almost Human, Except When It Matters: VoxParity and the Decisions a Voice Should Change
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A voice agent can handle almost every call on the words alone and still fail the few its sector's rules were written for. Emergency-call standards, fraud guidance, radio phraseology and vulnerability rules recognise that how a caller sounds, or what else is audible, can change the right action. VoxParity tests whether agents act on it. In 183 scenarios from 14 sectors, one transcript stays fixed while the audio changes (a coaching voice, a medical monitor beeping, a mayday under a radio check, noise over a drug name, a child's voice placing a bet, a frightened whisper), and with it the correct typed tool call. A words-only null test credits a system only if hearing the call moves its actions more than it moves a pipeline that only reads the words. Only 11 of the 23 systems that can also be run on the transcript pass. Descriptively, errors run toward the words: when the audio calls for protection, all 28 systems carry out the routine request more often than they over-react on clean calls (41% against 12% pooled; the words-only pipeline, 58% against 15%). Exploratory analyses place most of the leading systems' misses on cues they heard; systems beat the null almost entirely on items that state the rule; the leading systems overrule heard resignation or confusion far more often than acute alarm; and, in the models tested, describing the voice and stating the rule each recover part of the shortfall, leaving a gap on emotion.
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URL
https://arxiv.org/abs/2609.35922
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Jev in Medicine: A Benchmark Evaluation. Preliminary Results
2026-09-27 23:33:04Alfredo Madrid-Garc\'ia, Beatriz Merino-BarbanchoAbstract
Jev is a non-generative "System One" model that assigns probabilities to predefined answer options and cannot answer outside them. Its accuracy and calibration on medical question-answering and case-based diagnostic-reasoning tasks are unknown. We evaluated Jev 1.13 on four medical benchmarks: MetaMedQA, PubMedQA, DiagnosisArena-MCQ and the NEJM Case Challenges. GPT-6 Sol, with (medium) and without reasoning, was the reference. The primary outcome was top-1 accuracy; key secondary outcomes were calibration, selective prediction and recognition of unanswerable questions. All 8,469 requests returned a valid answer. Jev's accuracy was similar to that of GPT-6 Sol with medium reasoning on PubMedQA (78.4% vs 78.2%;), lower on MetaMedQA (74.8% vs 82.7%) and much lower on DiagnosisArena-MCQ (59.8% vs 82.4%;) and the NEJM cases (61.8% vs 82.4%). On MetaMedQA, Jev's probabilities were the best calibrated (expected calibration error 0.063 vs 0.146), and its answers with a probability of at least 0.9 (52.9% of questions) were 93.4% accurate, but GPT-6 Sol was as accurate when it accepted a similar proportion of questions. On DiagnosisArena-MCQ, Jev's probabilities discriminated poorly (AUROC 0.645 vs 0.768). Of the 162 questions whose correct answer was "I don't know or cannot answer", Jev chose that option for 10.5% (GPT-6 Sol, 8.6%). Median latency was 0.27-0.31 s; all 2,823 items cost USD 0.08. Jev was fast and inexpensive, and its accuracy was similar to that of a frontier LLM on research abstracts but lower on examination questions and much lower on complex diagnostic cases. Task-specific validation is required before clinical use.
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URL
https://arxiv.org/abs/2609.34024
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How Far Can INRs Go? Cross-Domain Parameter-efficient INR-Based Semantic Segmentation for Brain MRI
2026-09-25 17:35:07Ziyao Shang, Pouya Sadeghi, Letian Jiang, Alexander Wong, Sirisha RambhatlaAbstract
Biomedical image segmentation is central to medical image analysis, but practical deployment often faces limited annotations, memory constraints, and cross-site distribution shifts. Implicit Neural Representations (INRs) have recently emerged as a lightweight alternative for semantic segmentation, achieving competitive performance with substantially fewer parameters than conventional architectures. However, the mechanisms, scaling behavior, and domain generalization abilities of INR-based segmentation remain insufficiently understood. In this work, we study these questions in the context of cross-domain brain MRI segmentation. We analyze INR-based segmentation across low-parameter regimes, comparing it with conventional pipelines in both in-domain and out-of-domain settings. Surprisingly, we find that INR-based models do not simply improve with increasing parameter budget. Their advantage is most pronounced under low-parameter and limited-augmentation settings, while U-Net-based models benefit more from larger capacity and standard augmentation. We also investigate how INRs encode semantic information in their hidden features and show that complementary segmentation-relevant structure is distributed across multiple INR layers. Building on this insight, we introduce HierINRSeg, a hierarchical INR-based architecture that aggregates multi-layer representations for improved robustness and generalization. Extensive experiments show that HierINRSeg consistently outperforms MetaSeg, a strong recent INR-based segmentation baseline, with an average improvement of 5.6 percentage points in Dice for the in-domain test set and 8.2 percentage points out-of-domain. Overall, our analysis identifies the conditions under which INR-based segmentation is most effective, providing concrete guidance for model selection and future research.
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URL
https://arxiv.org/abs/2609.31573
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From Reward Signal to Visual Utility: A Controlled Audit of Medical VLM Post-Training
2026-09-25 16:06:54Wang JingxinAbstract
Medical vision-language model (VLM) post-training is commonly evaluated through answer accuracy. We examine how changes in accuracy and training objectives relate to image-conditioned decisions in a controlled Qwen2.5-VL-3B study on PMC-VQA. We compare supervised fine-tuning (SFT) with low-rank adaptation (LoRA) restricted to the language model, expanded multimodal adaptation scopes, standard answer-only Group Relative Policy Optimization (GRPO), and a counterfactual evidence objective. On 2,000 clean-test questions, language model LoRA SFT changes correct-image accuracy by +1.10 percentage points (95% paired bootstrap CI:-0.85 to +3.05), while visual-benefit events decrease by 2.40 points and image sensitivity decreases by 5.60 points. Paired records reveal 155 acquired and 203 lost visual-benefit events. Broader adaptation yields lower correct-image accuracy than language-model LoRA SFT. Standard GRPO produces mixed-reward groups and parameter updates, with an uncertain clean test accuracy change. A generation audit reveals that canonical option scores can follow a different token path from generated answers. With scores taken along the greedy generation path, the evidence target improves on the training set; its gains over standard GRPO remain inconsistent on validation data at matched training doses. Sample-level analyses trace how evidence scores, decision margins, and generated answers change during post-training. This empirical and measurement audit identifies gaps between optimization activity, target acquisition, and useful held-out visual behavior.
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URL
https://arxiv.org/abs/2609.31450
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ViSTA: A Simple Bridge Extends Visual Alignment to Clinical Time-Series Understanding in Multimodal LLMs
2026-09-25 16:06:29Junyi Gao, Yu Shi, Pingzhao Hu, Ewen M HarrisonAbstract
Clinical prediction models estimate risk from patient measurements, while large language models support medical text understanding and question answering. Yet their language capabilities do not ensure accurate prediction from structured, high-dimensional clinical time series. Improving this ability would connect risk estimation with flexible questions about a patient's evolving condition. We introduce ViSTA, a compact adapter that incorporates irregular numerical measurements into a pretrained vision-language model's chart representations. It learns corrections to visual tokens while leaving all pretrained parameters unchanged. On MIMIC-IV, ViSTA has the highest mean scores among the compared adaptations on all four metrics for acute kidney injury and mortality prediction across models with 2-9 billion parameters. With 0.516 million trainable parameters, the 2-billion-parameter model reaches an area under the ROC curve of 0.7376 for acute kidney injury, compared with GPT-5.6 Sol's 0.7380 with text input and high reasoning effort. Training for temporal question answering yields 69.27% accuracy at 4 billion parameters with over 90% fewer trainable parameters than low-rank adaptation using charts or numerical text, at a 2.82-4.88 percentage-point accuracy gap. ViSTA extends pretrained language models to numerical prediction and temporal questions.
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URL
https://arxiv.org/abs/2609.31448
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A Safety-Bounded SDC-to-MCP Gateway for Medical AI Agents
Abstract
The Model Context Protocol (MCP) provides a common interface through which AI applications discover and use external resources and tools. It allows language-model agents to ground their reasoning in current system state and interact with heterogeneous services. In medical environments, however, exposing device state and action affordances requires deterministic constraints on possible effects. We present an IEEE 11073 Service-Oriented Device Connectivity (SDC)-to-MCP gateway that exposes metrics, alarms, context references, and semantic metadata as read-only resources, while representing selected action affordances as policy-validated dry-run tools. The term safety-bounded denotes a narrow no-execution property: agent-facing requests dispatch no SDC device operation. A Python prototype supports simulated fault and lifecycle experiments, a software-reference protocol path spanning independent Java and Python implementations, deterministic baselines, representation ablations, and multi-model agent evaluation. The results show semantically explicit resource exposure, visible rejection of invalid or outdated state, and preservation of the no-execution boundary across resource, proposal, and authorization paths. Explicit semantic metadata improved conformity to required metric identifiers in structured alarm outputs relative to a generic representation, while retained structured-output failures reveal a distinction between plausible narrative answers and task-compliant machine-readable results.
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URL
https://arxiv.org/abs/2609.31358
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Open Vocabulary Domain Unlearning
2026-09-25 14:52:36Sumanth Udupa, Mehrtash Harandi, Yadan Luo, Mahsa BaktashmotlaghAbstract
Vision-Language Models (VLMs) exhibit remarkable zero-shot generalization, yet they often encode unwanted or hazardous stylistic domains such as idealized textbook diagrams in medical AI or cartoon vehicles in autonomous driving. Approximate Domain Unlearning (ADU) aims to selectively erase a model's recognition of a target visual domain while preserving accuracy on the remaining domains. However, existing ADU methods operate under a flawed closed-vocabulary assumption: they evaluate unlearning solely on the specific object classes seen during the unlearning fine-tuning phase. Consequently, these methods do not unlearn the domain itself; they merely overfit to seen class-domain pairs, leaving the domain easily recognizable for unseen classes and providing a false sense of removal. We argue that true domain erasure must be class-agnostic. To address this, we formalize Open-Vocabulary Domain Unlearning (OVDU), a rigorous protocol that mandates domain forgetting must transfer to held-out classes. To solve the OVDU challenge, we propose a surgical parameter-editing framework. First, a Fisher Information mask isolates domain-sensitive weights, mathematically protecting foundational zero-shot generalization. Second, our Targeted Manifold Scattering (TMS) objective uses preference-based mining to locally scatter the forget domain's stylistic geometry. Evaluated across PACS, OfficeHome, and DomainNet, our method vastly improves open-vocabulary generalization over existing baselines. Crucially, it delivers exceptional sample efficiency, outperforming peak 8-shot baseline results with only 4 shots.
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URL
https://arxiv.org/abs/2609.31356
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Stale-Document Poisoning: When Outdated Retrieval Overrides Correct Model Answers
2026-09-25 14:43:43Md Shamim Ahmed, Lukas Galke Poech, Richard R\"{o}ttgerAbstract
Retrieval-augmented generation (RAG) is often used to address outdated knowledge by providing external evidence. But retrieval helps only when that evidence is still valid. We identify a temporal alignment failure, stale-document poisoning, in which outdated evidence makes a model wrong despite answering correctly without retrieval. We construct a benchmark of 317 verified knowledge reversals across medicine, law, software, and platform policy, grounded in dated official sources. Across 12 models, recent medical reversals are harder than long-established ones. More importantly, outdated retrieval flips 30% of Llama and 37% of Qwen answers even without instructions to trust the document; explicit follow instructions raise these rates to 66% and 75%. Across four open models and four domains, poisoning ranges from 17-91%, while matched up-to-date evidence is followed in 97-100% of trials. To isolate temporal applicability, we keep the historical evidence unchanged across 50 reversals and vary only the evaluation date. A clear pattern emerges: dates alone produce only modest adaptation, but when models are explicitly told when the old evidence stops applying, the larger models switch to the appropriate answer almost perfectly. Causal interventions confirm that this validity information directly shapes the final decision. The same internal components also support broader comparison tasks, suggesting that temporal applicability can recruit a general reasoning mechanism used for other comparisons. Finally, a fixed recency-aware hybrid re-ranker reduces poisoning by 4.6-10.0 points when dates are accurate, with gains that depend on reliable temporal metadata. Reliable RAG therefore requires selective trust: models must determine not only what retrieved evidence says, but whether it still applies.
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URL
https://arxiv.org/abs/2609.31342
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PIA: A Personal Intelligence Agent Turning Health Conversations into Records and Records into Understanding
2026-09-25 13:32:20Jeonghun Yoon, Dongchan Kim, Hongyeon Yu, Young-Bum Kim, Jaegul ChooAbstract
General-purpose agent memory summarizes conversations: it extracts salient snippets, embeds them, and retrieves the top-k into the prompt. A health agent cannot run on summaries: a dose becomes a sentence, "since last week" is resolved at the model's discretion, and a three-month glucose trend cannot be answered by text similarity. We present PIA, a personal intelligence agent deployed alongside a consumer health agent. PIA receives the agent's natural-language requests, decides for itself whether and how to write or read, and turns conversations into typed clinical records and records into a synthesized understanding of the user. Its memory harness consists of four controls -- extraction, memory, retrieval, and understanding -- each a domain-agnostic mechanism with a pluggable health module: schema, medical alias dictionary, knowledge graph, and temporal rules. We show how the same query receives a different answer as the memory injected into the response context deepens from one-dimensional recall, to a two-dimensional health snapshot, to a three-dimensional trajectory with causality, and report lessons from operation: self-reported health data are missing not at random, question phrasing governs the quality of synthesized understanding, and nearly a third of candidate causal links are structural noise that rules alone remove.
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URL
https://arxiv.org/abs/2609.31255
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ReG-SAM: Reference Graph-Driven SAM for 2D Foundational Vessel Segmentation
2026-09-25 11:53:31Donghang Lyu, Zichen Zhang, Oleh Dzyubachyk, Marius StaringAbstract
Vessel segmentation in medical images is essential for many clinical tasks, ranging from diagnosis to treatment planning. However, it remains challenging due to complex vascular morphology and diverse imaging conditions. Existing deep learning methods rarely aim at building a generalizable vessel segmentor across anatomies and modalities. While the Seg- ment Anything Model (SAM) has shown promise for med- ical image segmentation, its original design does not fully exploit vascular morphology and struggles with fine-grained vascular structures, leading to suboptimal performance. In this paper, we propose ReG-SAM, a SAM-based framework tailored to 2D vessel segmentation that leverages reference graph set for enhancing vascular representations. Specifically, we introduce two modality-aware representations derived from the reference masks: graph prompt embeddings (GPEs) that encode global spatial features from graphs, and vascu- lar prototype embeddings (VPEs) that capture fine-grained modality-specific vessel characteristics from multi-scale fea- ture maps and vascular masks. Since both require vascular masks that are unavailable during inference and require robust modality-aware vascular feature representations, we construct a modality-wise vascular database and develop two reference graph-guided representation learning schemes for estimating GPEs and VPEs using samples from the database rather than ground-truth masks. Extensive experiments across 19 datasets demonstrate that ReG-SAM consistently outperforms existing baselines, even those using manual prompts, particularly on challenging thin vessels.
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URL
https://arxiv.org/abs/2609.31160
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Quantum Diffusion Models for Medical Image Analysis
2026-09-25 10:10:11Francesco Aldo Venturelli, Stefano Martina, Marco Parigi, Filippo Caruso, Alba Cervera-Lierta, Miguel A. Gonz\'alez BallesterAbstract
Quantum Machine Learning is a novel field of research aimed at devising machine learning approaches exploiting principles of quantum mechanics, such as superposition, entanglement and interference. In this context, we present a scalable hybrid Quantum Diffusion Model, and evaluate its use for medical image analysis. Specifically, our method is based on a Discrete-Time Quantum Walk algorithm, executed on a real quantum device, to model the forward dynamics of the diffusion model. For the backward step of the diffusion model, we devise and evaluate a classical learning model, which is used to reversely denoise the data. In contrast with other existing attempts at applying quantum machine learning for image analysis tasks, severely limited by the size of existing quantum devices, our method allows to process real-world large size medical data. In particular, we present results on grayscale and RGB images, as well as 3D volumes of moderate sizes. We benchmark our results by reproducing an alternative classical counterpart model, based on diffusion models on discrete state spaces. By doing so, we compare the generation capabilities of both models in terms of three distinct state-of-the-art metrics in the field of image generation, showing the competitive, promising results of our approach.
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URL
https://arxiv.org/abs/2609.31070
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CG-Probes: Recovering Guardrail Directions from Patient Query Embeddings
2026-09-25 10:01:13Marko \v{R}eh\'a\v{c}ek, V\'it\v{e}zslav Du\v{s}ek, Martin Rusinko, V\'it Nov\'a\v{c}ekAbstract
Patient-facing AI assistants promise valuable support to patients, but incoming queries can pose medical risks. To create guardrails, we work with oncologists to define three ordinal risk axes: Medical Urgency, Psychological Urgency, and Topic Sensitivity. We propose Clinical Guardrail Probes (CG-Probes) to measure the risks from query embeddings. We probe for each axis in the normalized embedding space of frozen embedders via the difference-in-means method, treating each axis as a potential linear direction. To train the probes, we cluster 79,658 Czech oncology search queries with BERTopic and use these clusters to generate pairs of queries with contrastive risk levels via few-shot prompting. We evaluate the approach on 200 queries (90 real, 110 synthetic), each graded by two oncologists, against two open-weight LLMs and a frontier LLM. We find that urgency-based axes are recoverable as linear directions, and the probes are competitive with open-weight LLMs (no significant differences in quadratic-weighted kappa) at a fraction of the latency. Each axis yields a scalar score that clinicians can inspect and use to set escalation thresholds. The pipeline requires only search logs, axis definitions, and black-box access to the embedding model, suggesting transferability across healthcare domains. Robust validation on new queries and axes remains future work.
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URL
https://arxiv.org/abs/2609.31062
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UltraG-Bench: A Multi-task Benchmark for assessing Large Vision-Language Models on Pixel-level Evidence Grounding in Ultrasound
2026-09-25 07:43:12Quanhao Zhu, Bo Xu, Rui Lin, Chenyuan Wang, Yu Shao, Boling Zhu, Jiuyan Sun, Liang Zhao, Hongfei Lin, Feng XiaAbstract
Ultrasound is one of the most widely used medical imaging modalities, and recent large vision-language models(VLMs) have shown increasing capabilities in ultrasound image understanding. However, these models fail to provide pixel-level visual evidence aligned with their semantic predictions, and their fine-grained grounding capability in ultrasound remains largely unclear. We introduce UltraG-Bench, a large-scale multi-task benchmark for evaluating pixel-level evidence grounding in ultrasound. UltraG-Bench is built by annotating 40 public ultrasound segmentation datasets spanning 13 anatomical categories, and comprises three progressive tasks: instruction-guided segmentation, evidence-grounded VQA, and evidence-grounded report generation, with 331125, 666779, and 138832 annotations, respectively. Comprehensive evaluation of 14 state-of-the-art models reveals a substantial gap between semantic understanding and fine-grained pixel-level localization. We further propose UltraG-Agent, which combines the semantic reasoning capabilities of a VLM with the ultrasound-specific segmentation capability of UltraSAM3. Experiments show that UltraG-Agent substantially improves both semantic prediction and pixel-level visual grounding. Our dataset and code are available at this https URL.
Abstract (translated)
URL
https://arxiv.org/abs/2609.30928
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Effects of Transcript Compression on LLM-based Medical Misinformation Detection in Japanese YouTube Videos
2026-09-25 06:42:44Yuya Wake, Sho Tsugawa, Toshiyuki AmagasaAbstract
Large language models (LLMs) are increasingly used to assess long-form medical videos, but their effectiveness may depend on whether transcripts are provided in full or compressed through summarization, retrieval, or claim screening. This study examines how such transcript compression affects LLM-based veracity classification of Japanese medical YouTube videos. We compare four transcript input designs: full transcripts, LLM-generated summaries, RAPTOR-based retrievalaugmented generation (RAG), and Screening, which extracts candidate medical and health-related sentences. Using 74 long-form videos labeled as Real or Fake, we evaluate classification performance and analyze linguistic changes using J-LIWC, hedge expressions, and institutional or technical terms. The full-transcript Baseline achieved the best performance, whereas all compressed inputs increased false negatives, meaning that Fake videos were more likely to be misclassified as Real. Summary caused the largest performance drop, while Screening performed best among the compressed inputs but still omitted many medically relevant sentences. Linguistic analyses showed that these errors were not explained by a simple increase in certainty. Instead, Summary reduced affective, social, temporal, cognitive, and conversational cues, while Summary and RAG made institutional and technical terms more salient. These findings suggest that transcript compression can represent Fake videos as more coherent and authoritative inputs, thereby weakening cues needed for misinformation detection
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URL
https://arxiv.org/abs/2609.30882
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Partial AUC Maximization from Positive-unlabeled Data
2026-09-25 03:43:39Atsutoshi Kumagai, Tomoharu Iwata, Taishi Nishiyama, Hiroshi Takahashi, Kazuki Adachi, Yasuhiro FujiwaraAbstract
The partial area under the receiver operating characteristic curve (pAUC) is an important performance metric for binary classification that summarizes true positive rates within a specific range of false positive rates (FPRs). Classifiers that achieve high pAUC need to be obtained in many real-world applications such as cybersecurity, medical care, and advertising. Although many methods for maximizing the pAUC have been proposed, they typically require both labeled positive and negative data for training. However, in practice, labeled negative data are often difficult to collect due to privacy concerns or the need for high expertise to annotate them. In this paper, we propose a method for maximizing the pAUC from positive and unlabeled (PU) data without negative data. Within an empirical risk minimization framework, we show that the pAUC, including its FPR-dependent thresholds, can be represented using only the positive and marginal densities, and derive an empirical estimator from PU data. A classifier is then trained by maximizing the derived smoothed empirical pAUC estimator. We experimentally demonstrate the effectiveness of the proposed method with ten real-world datasets.
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URL
https://arxiv.org/abs/2610.00284
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