Large language models (LLMs) have been explored as surrogates for human survey respondents. A more promising application is data augmentation, where LLMs predict new responses from partial human data. However, the semantic similarity between questionnaire items is a known source of correlation between answers. It is thus unclear whether LLMs actually infer meaningful relationships between question-response pairs, or use surface-level comparison between questions as a heuristic. To assess this, we evaluated how three LLMs can predict responses to held-out items in two surveys measuring attitudes toward automated or light-electric vehicles, based on varying proportions of known responses. Performance was compared to two baselines, where new responses were derived by maximizing embedding-similarity to a prior response. While LLMs mostly predicted human responses better than baselines, their performance consistently declined with a lower share of known responses, even aligning with the baseline in one survey. Our results show that LLMs' capacities for augmenting replies varied across surveys, and can revert to the same levels as simpler embedding similarity baselines when less data is available.
https://arxiv.org/abs/2610.29645
Automatic phenotype information extraction plays an important role in rare disease diagnosis, genotype-phenotype analysis, and precision medicine. However, accurately identifying phenotype concepts and determining their associations with specific patients remain challenging, particularly in full-text biomedical articles involving multiple patients and complex clinical descriptions. This paper presents an overview of CHIP 2026 Shared Task 1, which aims to promote the development of methods for patient-specific phenotype concept recognition from full-text biomedical literature. The task consists of two subtasks: full-text phenotype concept recognition and patient-specific phenotype association. For this evaluation, we used 200 annotated full-text biomedical articles from the PatientPheX dataset, containing 506 patients, 15,193 phenotype mentions, and 5,656 patient-phenotype associations. A total of 455 teams registered for the competition, with 189 and 103 valid submissions received on the Phase A and Phase B leaderboards, respectively. The best-performing system achieved an overall score of 0.7389 on the final test set, outperforming the baseline by 8.37 percentage points. The top-performing teams explored diverse approaches combining biomedical language models, large language models (LLMs), and ensemble strategies. The evaluation results highlight both the potential of these approaches and the remaining challenges in patient attribution and phenotype normalization from full-text biomedical literature. The post-evaluation phase remains open at this https URL.
https://arxiv.org/abs/2610.29606
Diffusion language models generate by iteratively denoising a masked sequence under bidirectional attention, without the strict left-to-right commitment of autoregressive decoding. Whether this difference affects how reliably they remain grounded in structured inputs is largely unexplored. We study this question in table-to-text generation using ToTTo, where highlighted source cells make factual grounding directly testable. We compare the masked diffusion models MDLM and LLaDA with GPT-2 and GPT-Neo under an identical retrieval-based few-shot protocol, together with a QLoRA-adapted LLaDA, and we score reference similarity and source grounding as separate axes. The two pull apart. Within LLaDA, additional demonstrations raise BLEU from 11.3 to 22.0 while NLI entailment against the source table falls from 0.78 to 0.52; QLoRA reaches the best BLEU of the study, 24.15, and grounds no better for it. Manual annotation shows the failure modes differ in kind: the autoregressive baselines tend to wander off the table, while LLaDA-based models more often stay on topic and swap out individual entities. Reference-based metrics alone are insufficient to assess faithfulness in table-to-text generation.
https://arxiv.org/abs/2610.29602
Vision-language models (VLMs) achieve remarkable performance on 2D medical images, such as X-rays or pathology images, while 3D VLMs that directly process CT/MRI volumes lag behind due to limited 3D training data and the predominance of 2D foundation architectures. To leverage powerful 2D VLMs for analyzing medical volumes, which contain hundreds of slices, it is therefore necessary to focus only on those few slices, which are diagnostically relevant. To enable such a prioritization, we propose XGLASS, a method that transfers medical expertise from 2D X-rays to 3D CT for task-aware slice prioritization. XGLASS uses disease-conditioned importance maps derived from language-aligned radiologist gaze on X-rays and spatially aligns them with coronal CT projections, bringing gaze priors and CT content into a shared 2D representation. The fused gaze-prior/CT projection is then used to predict a disease-specific ordering of axial slices, prioritizing diagnostically relevant slices. XGLASS significantly improves budgeted retrieval over 2D and 3D-native baselines, achieving a top-10 hit rate up to 75.9% for the best-performing disease. In practice, this means that after inspecting only the top 10 slices (4.17% of a 240-slice scan), XGLASS identifies a diagnostically relevant slice in more than 75% of cases. For downstream slice-wise finding classification, an XGLASS-selected 30-slice candidate set reduces model calls by 87.5% while improving F1 by 11.3 percentage points over all-slice inference, 4.2 points over the strongest 2D selector, and remains competitive with 3D-native selectors while requiring up to 130.8 times less time and 10.9 times less GPU memory per finding, supporting its use as a lightweight preselector for volumetric CT analysis. The code and pretrained checkpoint are available on this https URL.
https://arxiv.org/abs/2610.26255
Aligned large language models are trained to comply with benign requests while refusing harmful ones. However, recent work shows that this refusal behavior is fragile and can often be disrupted by simple activation- or weight-space interventions. In particular, refusal has been shown to be largely mediated by a single residual-stream direction, typically computed as a difference-of-means vector between harmful and harmless prompts. However, this standard construction aggregates heterogeneous harmful prompts into one uniform average, potentially conflating distinct refusal-related phenomena. In this work, we study whether refusal interventions can be strengthened by learning how to combine prompt-specific refusal directions. We propose Weighted Refusal Direction Optimization (WRDO), a procedure that constructs a composite refusal direction from a bank of per-prompt directions using learned aggregation weights. This approach allows different harmful prompts to contribute unequally to the final intervention direction. We evaluate WRDO against prior single-direction methods on three open-weight language models using three guard judges and HarmBench as an external evaluator. We further measure the effect of the intervention on general model capability through standard utility benchmarks. Finally, we investigate a defense-oriented setting in which the same optimization machinery is used in reverse to restore refusal behavior in an abliterated model checkpoint. Our results show that weighted aggregation provides a more effective and flexible mechanism for manipulating refusal representations.
https://arxiv.org/abs/2610.29555
Fine-grained multimodal intelligence requires models to both understand a designated region and localize it from language. Existing methods learn these directions with separate objectives and task-specific annotations. We present Generalized CycleGRPO, the first unified reinforcement learning framework coupling region understanding and localization across spatial, temporal, and spatio-temporal domains. Given a region, a multimodal large language model generates candidate descriptions and then localizes each description to reconstruct the input region. Reconstruction overlap provides a verifiable reward for captioning, while individual localization rewards improve the inverse mapping. A common region-space formulation extends this cycle from image masks and boxes to video intervals and timestamped spatial evidence, without reference captions or an external language-model judge during reinforcement learning. In videos, the cycle encourages descriptions that distinguish a target event from similar recurrences. We introduce DOVE (Distinctive Occurrence-level Video-caption Evaluation), a human-verified contrastive benchmark for this temporal distinctiveness. CycleGRPO improves SAMTok's overall gIoU from 57.5% to 68.2% on GroundingSuite and average gIoU from 71.2% to 78.7% on GRES. For temporal tasks, it achieves 51.9% tIoU on Charades and 33.3% Temporal Evidence Coverage on DOVE, compared with 45.6% and 14.8% for the Qwen3-VL initialization. These results establish region-text cycle consistency as a general self-evaluation principle for multimodal understanding and localization. Models, code, and DOVE are available at this https URL.
https://arxiv.org/abs/2610.29552
Linear-attention language models keep their context in a recurrent state of fixed size, where an inference system stores one copy of this state for every sequence it decodes at the same time. Storing the state at lower precision therefore lets more sequences share an accelerator. Existing state quantizers round the state after every generated token and report that four bits lose accuracy unless the bit width is raised or the model is fine-tuned.\par We introduce PACE, a post-hoc four-bit state quantizer. PACE rounds the state only once every few generated tokens, as chunked kernels already do once per chunk during prefill, and keeps the tokens generated in between in a small buffer. Rounding less often reduces the error that accumulates in the state. Additionally, we find that the large entries of the gated-delta state gather in columns, because some channels of the update written at each token remain large across many tokens. PACE therefore shares each quantization scale within one column. It also keeps the heads that retain rounding error longest at eight bits. On four hybrid models from 4B to 35B parameters, PACE with mixed four- and eight-bit heads is competitive with eight-bit DAMP on the three larger models at about two thirds of its memory, PACE with four-bit heads throughout scores higher than Q-Mamba at equal memory, and rounding every few tokens preserves the decoding speedup of the buffer.
https://arxiv.org/abs/2610.29545
Multi-modal Large Language Models (MLLMs) have seen broad adoption, but their biases are still far less examined than those of standard LLMs, creating possible social harms when deployed in real-world settings. Prior efforts to extend bias analyses from LLMs into the multi-modal space either cover only a few bias categories or do not ensure that the groups being compared are clearly addressed by visual cues in the images. To overcome these limitations, we introduce Melange, a wide-ranging synthetic visual benchmark covering seven categories for assessing social biases in MLLMs. It is grounded in the widely used language-only BBQ dataset (Bias Benchmark for Question Answering) from BigBench, carefully extending its constructed contexts via controlled generation of visual scenarios so the target attributes appear visually and clearly. To maximize reliability, our generated images pass through two stages of validation: automated screening using visual question answering (VQA) and subsequent manual inspection by human annotators. By systematically evaluating 23 open-source MLLMs across three matched evaluation settings---text-only, image-only, and image-with-context---Melange isolates the fairness effect of the input modality. Switching from text to vision reduces fairness by 0.291 on average, a gap that varies by model family rather than by scale alone. A perception control confirms that this gap is not an artifact of visual comprehension: models identify the depicted attributes at 90--95\% accuracy yet still fail to abstain. When models do commit to a biased answer, polarity-aware stereotype alignment shows they choose the human-stereotypical response roughly three-quarters of the time.
https://arxiv.org/abs/2610.29537
Masked language modelling (MLM) is the dominant pretraining objective for transformer encoders applied to longitudinal electronic health records (EHRs). However, reconstructing individual events may overemphasise noisy or weakly informative observations and does not explicitly encourage learning higher-level patient states. Joint-Embedding Predictive Architectures (JEPAs) instead learn by predicting representations in latent space and have shown strong performance in a variety of domains. In this paper, we investigate to what extent JEPA can be adapted to EHR sequence representation. Our empirical investigation using MIMIC-IV shows that although all three of our JEPA formulations train stably without representational collapse, they consistently underperform standard MLM. We find that target size, not target heterogeneity, increases prediction error, yet reducing the target size does not recover downstream performance. This suggests that stable latent prediction alone is insufficient for competitive EHR representation learning and highlights the challenge of defining clinically meaningful latent targets for EHR.
https://arxiv.org/abs/2610.29528
Speculative decoding accelerates large language model inference by employing a compact draft model to propose candidate tokens that are verified in parallel by a target model. Conventional training relies on soft-label distillation, which forces the draft model to mimic the target's full output distribution, including high-entropy regions that degrade acceptance rates and increase early rejection risk. We propose RCSD (Reinforcement and Continual Learning for Speculative Decoding), a training framework that aligns draft model optimization with the system-level objective of maximizing acceptance length. RCSD leverages naturally occurring accepted and rejected sequences during speculative inference to construct implicit preference pairs, with masked loss to avoid penalizing target-aligned tokens. Evaluated across multiple benchmarks, RCSD improves average acceptance length by 35% over HASS and achieves 1.35x faster end-to-end inference than HASS on practical workloads, without compromising generation quality.
https://arxiv.org/abs/2610.29527
Retrieval-based in-context learning (ICL) enables large language models (LLMs) to predict tabular labels from similar examples, but it remains unclear whether LLM inference improves on direct voting over those same examples. We address this question by comparing four general-purpose LLMs with distance-weighted nearest-neighbor voting (Distance-KNN) using identical retrieved neighbors across 19 tabular classification datasets. With the number of demonstrations fixed, enlarging the retrieval candidate pool improves accuracy for all predictors, yet Distance-KNN achieves the highest mean accuracy at every pool size. More detailed analyses reveal that LLM gains are concentrated where retrieved neighbors exhibit low label consensus and vary across models. These gains further depend on the average feature-space distance to the test query: under low label consensus, some LLMs outperform Distance-KNN in close and intermediate neighborhoods, but all fall behind on average in the most distant group. Complementary experiments on the number of demonstrations, prompt formulation, retrieval representation, and label-balanced demonstration selection largely preserve the overall findings. These results characterize when LLM inference adds predictive value beyond distance-weighted voting in retrieval-based tabular ICL.
https://arxiv.org/abs/2610.29520
While Chain-of-Thought (CoT) prompting improves the reasoning performance of large language models (LLMs), recent studies have shown that final answers do not always depend on the generated rationales. In particular, LLMs may rely on query-specific shortcuts rather than the information provided by their reasoning steps. In this paper, we investigate whether context-aware decoding (CAD), an existing contrastive decoding method, can mitigate such shortcut behavior when applied to CoT reasoning. We study this application as Rationale Contrastive Decoding (RCD), which contrasts the next-token distributions conditioned on the query with and without its rationale, amplifying tokens whose likelihood increases due to the rationale. We provide a theoretical interpretation of this decoding rule via a KL-regularized reward-maximization objective. Experiments across five reasoning benchmarks demonstrate that RCD improves answer accuracy over standard CoT. Furthermore, intervention analyses using ground-truth and random rationales reveal that RCD increases the behavioral dependence of final answers on the rationale content. Our findings suggest that contrastive decoding offers a simple, training-free approach to mitigating query shortcuts.
https://arxiv.org/abs/2610.29518
Recent advances in large language models (LLMs) have demonstrated transformative potential across diverse fields. However, in computer-aided synthesis planning (CASP), current LLM methodologies are often restricted to single-molecule representations, limiting their application to isolated, single-task scenarios such as precursor prediction. Addressing this gap, we present ChemBART, a BART-based language model that adopts a reaction-centric pre-training strategy. By leveraging a mask-filling pre-training task on holistic reaction expressions (Reactant > Reagent > Product), ChemBART effectively solves a variety of chemical problems, including precursor/reagent generation, temperature-yield regression, and molecular property classification. Building on these capabilities, we demonstrate the integration of ChemBART with Monte Carlo tree search (MCTS) for multi-step synthesis route design, where the model serves to optimize the policy and value functions within a reinforcement learning framework. Beyond single-molecule pre-trained LLMs that are constrained to specific applications, ChemBART unifies diverse chemical tasks to facilitate synthesis planning with comprehensive implementation information. Most significantly, the proposed multi-step synthesis routes and reaction conditions were validated in the wet lab, confirming the discovery of shorter synthetic pathways with a >20% yield improvement over established literature benchmarks. Our work highlights the potential of reaction-focused pre-training and showcases the broad utility of ChemBART in closing the loop between in silico prediction and wet-lab synthesis.
https://arxiv.org/abs/2601.02915
Parallel thinking has emerged as a promising paradigm for enhancing the reasoning capabilities of Large Language Models (LLMs) by exploring multiple reasoning paths simultaneously. However, we identify that parallel thinking via Reinforcement Learning (RL) typically suffers from the mode collapse of reasoning paths, where parallel thinking trajectories degenerate into similar ones. This homogeneity undermines the fundamental motivation of parallel thinking, that is, maintaining multiple hypotheses concurrently to prevent premature loss into a suboptimal solution. In this paper, we propose Diverse Parallel Thinking (DPT), a simple yet effective RL approach for parallel thinking designed to encourage path diversity. DPT rewards the model to develop distinct reasoning strategies by penalizing the prefix similarity of parallel thinking paths, thereby enhancing a more comprehensive exploration of the reasoning space. We conduct various experiments and analyses across multiple reasoning benchmarks to demonstrate the effectiveness of DPT. Results show that DPT successfully outperforms previous parallel thinking methods, achieving state-of-the-art performance over baselines. We validate path diversity as a key element to improve parallel thinking. Our code is available at this https URL.
https://arxiv.org/abs/2610.29501
Biometric recognition often degrades under partial facial vis- ibility, where conventional facial cues are occluded. The forehead region remains consistently visible and contains distinctive crease patterns that can serve as a complementary biometric trait. We present a unified eval- uation of forehead-crease recognition across explainable zero-shot rea- soning, domain-adaptive learning, and trait-specific modeling. FIRE en- ables interpretable zero-shot verification using multimodal large language models, while pretrained face-recognition models are adapted to the fore- head domain through margin-based learning. Under open-set evaluation, the best zero-shot model GPT-4o+FIRE achieves 18.22% EER, while Edge-Forehead achieves 8.30% EER and 54.01% TMR@0.1% FMR. The results show that although MLLMs offer interpretable zero-shot verifi- cation, trait-specific learning remains more effective for robust forehead- crease biometric recognition.
https://arxiv.org/abs/2610.29495
Guard models support the safe deployment of language model agents, but fixed risk taxonomies limit their ability to accommodate requirements that vary across applications and tasks. Under user-defined policies, detecting violations requires interpreting both the applicable rules and the agent's behavior, since identical actions can receive different judgments under different policies. To support learning this capability, we introduce AdaptiveSafety, a dataset of 10,939 training examples and 1,000 test examples covering policies with 1--100 rules. The dataset combines trajectories from multiple sources with policy and behavioral counterfactuals, pairing each example with an explanation and the complete set of violated rules. These counterfactuals expose changes that alter compliance, while structural augmentations provide supervision for consistency under rule reordering and identifier remapping. Building on this supervision, we propose SafePO, a reinforcement learning algorithm for refining violation identification while balancing explanatory reasoning and final verdicts. SafePO uses structured rewards to assess prediction correctness, retains group-relative advantages at the response level, and employs a separately trained value model to modulate token weights within explanation and verdict regions. Separate normalization controls their relative contribution to training despite differences in length. Through supervised initialization followed by SafePO, we develop AdaGuard, a family of 0.6B, 4B, and 8B guard models that assess agent trajectories under policies supplied at inference time. Our 4B model achieves binary accuracies of 89.30\% on AdaptiveSafety and 71.82\% on DynaBench. The project repository is available at this https URL
https://arxiv.org/abs/2609.34241
Codes of professional ethics guide and restrict specialists, who increasingly work with assistants built on large language models. Such an assistant can breach the user's code, or help the user breach it, without the user noticing. Evaluations reporting broad categories of harm cannot show how often this happens or which provision is breached. TenetBench pairs 3,433 requests conflicting with clauses of fifteen Russian-language professional codes with benign twins that differ only in the legitimacy of what is asked. An automated pipeline generates the tasks from the text of a code, so the corpus grows with every code added and a provision yields new tasks on every run. It also produced tasks and human-validated verdicts from two English codes of other jurisdictions. In human validation of the frozen pipeline, specialists rated 0.995 of the conflicting tasks plausible, and the model judge agreed with the adjudicated label at Gwet's AC1 of at least 0.894 on 1,860 elements. We evaluated fourteen model and reasoning-mode combinations on whether they produce the conflicting text, decline or warn. Eleven of the fourteen produce conflicting content on most such requests, mostly without a warning, and nearly three warnings in four accompany conflicting content. The models that conform more do so by declining while still serving the legitimate twin, and enabling reasoning halved the refusals of two models. We hope the dataset and pipeline will help evaluate how language models observe professional norms and let diagnostic datasets be built for particular professions and organisations.
https://arxiv.org/abs/2610.29477
Large language models (LLMs) have shown great potential as general-purpose user simulators for interactive systems. Prior studies have demonstrated that training on high-quality data can substantially improve model reasoning and downstream task performance. However, the upper bound of user simulation is still constrained by the model's reasoning paradigm: native chain-of-thought often degenerates into shallow pattern matching and fails to adequately model the behavioral factors underlying real user decisions. In this paper, we propose OmniSimulator, a novel training framework designed to improve the predictive ability of small LLMs for realistic user simulation on short-video platform environments. Specifically, OmniSimulator organizes behavior-oriented reasoning through a structured schema with five dimensions, carefully selects data from real user-behavior scenarios, and introduces a teacher model to generate high-quality reasoning traces under the proposed schema, helping small models learn behavior-relevant reasoning patterns rather than relying on superficial behavioral correlations. Based on this process, we construct 9,881 high-quality training instances from three months of historical interaction trajectories of 200 real users, averaging about 50 distilled examples per user. Experimental results show that OmniSimulator improves the average score of Qwen3-8B by 34.33%, achieves performance competitive with Claude-Sonnet-4.5, and supports smaller-scale, self-hosted deployment. These results suggest that learning structured behavior-oriented reasoning patterns is a promising direction towards scalable and high-fidelity LLM-based user simulation.
https://arxiv.org/abs/2610.29472
Omni-modal large language models (LLMs) have achieved remarkable progress in audio and video understanding. However, existing models struggle with long-form, multi-speaker videos, especially in understanding the entire video and recognizing who says what and when. To characterize the capability limit of current omni LLMs and guide future model development, we introduce Omnilingual-MsASR, a multilingual, multimodal benchmark for long-form Multi-speaker Automatic Speech Recognition (MsASR) covering six languages, recordings up to 30 minutes, and scenarios with up to 20 speakers. Omnilingual-MsASR provides parallel audio and video inputs to evaluate models' cross-modal consistency and their ability to exploit complementary cues across modalities. Extensive evaluations of leading omni-modal LLMs reveal substantial performance bottlenecks, while their tcpWERs frequently exceed 100%. These findings highlight fine-grained temporal localization, speaker disambiguation, and cross-modal synergy as key challenges for future omni-modal foundation models. Our work is available at this https URL.
https://arxiv.org/abs/2610.29455
Large language model (LLM) agents increasingly use tools to complete tasks in stateful environments. However, many training environments remain largely static apart from changes caused by the agent's own actions, whereas external events introduced by other users, services, or sudden contingencies in real environments can invalidate ongoing plans. To address this gap, we introduce DynaWeave, an automated synthesis framework that transforms existing static tasks into verifiable dynamic scenarios. The framework generates exogenous events relevant to each task, covering changes in task requirements, environment state, and external information. It uses directed acyclic graphs (DAGs) to represent dependencies between events and an execution engine to activate them during agent interaction. A dynamic verifier revises only the evaluation checks affected by events that actually occur and retains all other checks. Using DynaWeave, we collect 2,095 verified interaction trajectories across 36 environments and use them for supervised fine-tuning of Qwen3.5 models. Experiments on Gaia2, CostBench, and ToolMaze show that DynaWeave achieves consistent improvements in overall performance across all three evaluated model sizes, increasing the task completion rate on CostBench by 67.34 percentage points and even exceeding the performance of Gemini-3.1-Pro-Preview on ToolMaze. These results support dynamic scenario synthesis as a practical approach to training agents to adapt to changing environments. Our code is available at this https URL.
https://arxiv.org/abs/2610.29443