Cervical vertebral maturation (CVM) assessment plays a pivotal role in orthodontic diagnosis and determining the optimal timing of treatment, especially for pediatric patients. In this paper, we propose LM-PCVMNet, a novel deep learning framework for automatic pediatric CVM staging. Specifically, our method integrates vertebral anatomical landmark information, heatmap-guided feature modulation, and metadata-informed similarity modeling into a unified learning framework. We introduce a heatmap-guided feature modulation module that enhances feature extraction by leveraging landmark-centered heatmaps to highlight morphologically relevant vertebral regions. A vertebral landmark-prompting block is designed to incorporate anatomical geometry into the representation learning process. Furthermore, we develop a learnable metadata supervised contrastive loss that adaptively modulates positive-pair similarity based on metadata similarity, enabling the model to learn more biologically consistent and discriminative features. To facilitate further research in pediatric orthodontic treatment, we additionally release PCVM+. It contains 1800 lateral cephalometric radiographs from real-world patients aged 3-15 years, with expert-annotated CVM stages, 13 vertebral anatomical landmarks, and corresponding metadata. We perform comprehensive experiments on two datasets, and the results show that our method achieves state-of-the-art performance, effectively improving landmark localization and classification accuracy over existing models. Code and dataset will be available at this http URL.
https://arxiv.org/abs/2609.16033
Deep learning on cortical surfaces faces a dilemma: capturing the complex topology of over 60 nomenclature-dependent sulci per hemisphere requires high-capacity models, yet the extreme scarcity of expert annotations ($N=62$ subjects) inevitably causes overfitting. Standard supervised approaches fail to generalize in this data-scarce regime, particularly for variable and small sulci where topological ambiguity is high. To overcome this limitation, we introduce a Geometric-to-Semantic Spherical Transfer Learning framework. First, we leverage massive unlabeled data (UK Biobank, $\approx$30,000 subjects) to pre-train a spherical encoder using a locally-optimized strategy. By relying solely on continuous surface features (curvature and depth), the relevance of this pre-training is confirmed by the model's ability to detect localized and rare topological traits, such as sulcal interruptions. The downstream labeling task, however, introduces extracted sulcal fundi (lines) as an explicit semantic input. To bridge this dimensional domain gap (from purely geometric to semantic) without causing catastrophic forgetting, these anatomical lines are integrated into the pre-trained backbone via a soft-initialized Topological Prior Injector. Our experiments demonstrate that this approach outperforms fully supervised baselines trained from scratch, achieving a mean Dice of 0.77. Crucially, a local analysis reveals that the self-supervised geometric priors yield the largest performance gains on variable and tertiary sulci (up to 14.8%), confirming that learning the cortex shape is highly beneficial for identifying its rarest parts.
https://arxiv.org/abs/2609.12627
Automated landslide segmentation on Mars is one of the important tasks for understanding its surface processes, and all will aid in future space exploration. However, it remains a relatively underexplored open challenge because landslide morphology is highly variable, foreground regions are often sparse or irregular, and orbital observations combine heterogeneous spectral and topographic cues. In this context, this work investigates the capability of deep learning to address Martian landslide segmentation through an extensive assessment of modern neural segmentation models. To the best of our knowledge, this is the first study to provide such a comprehensive exploration in this domain. We further propose TransCPLES, a U-shaped network that couples Contextual Progressive Layer Expansion feature extraction with Transformer-based contextual reasoning, enabling the model to capture local geomorphic patterns and broader spatial dependencies for more reliable landslide delineation. Experiments on MMLSv2, a seven-band multimodal Martian landslide dataset, show that TransCPLES achieves the best overall performance when evaluated on geographically distinct samples, with consistent delineation across different landslide extents, stable foreground discrimination, and a favorable balance between accuracy and computational cost compared with several state-of-the-art convolutional, attention-based, and Transformer-based segmentation models. With this work, we hope to provide a useful reference and encourage further research and development in deep learning for planetary remote sensing. Code will be available after publication.
https://arxiv.org/abs/2609.13332
Ultra-low-dose computed tomography (ULDCT) reduces radiation exposure but suffers from severe noise that degrades diagnostic image quality. Existing deep learning-based denoising methods are typically trained in an organ-specific fashion, resulting in limited generalization across heterogeneous multi?organ imaging scenarios. Foundation models present a promising all-in-one paradigm for unified multi-organ denoising. However, their architectures suffer from poor interpretability and rely on heuristic training strategies. To address these limitations, we propose an architecture?interpretable foundation model based on the deep dictionary network (DDN) for unified multi-organ ULDCT denoising. Inspired by multilayer sparse representation theory, DDN cascades convolutional sparse coding layers with iterative soft-thresholding, providing inherent architectural interpretability. Furthermore, a dynamic dictionary module and a threshold generation module are embedded within each layer to enhance representation ability. We conduct DDN pre-training on more than one million multi-organ normal-dose CT images by recovering clean images from Gaussian-noised inputs. Sparse regularization is additionally imposed on latent feature representations, guiding the network to learn compact and noise-robust priors. The complete architecture is jointly fine-tuned on multi-organ ULDCT datasets, enabling a single unified model to perform denoising across diverse anatomical regions. Extensive experiments validate that our proposed method achieves state-of-the?art performance and consistently surpasses competing ULDCT methods across all mul
https://arxiv.org/abs/2609.16031
Automated crack inspection increasingly relies on deep learning, yet its reliability is limited by scarce and weakly controllable defect data. Existing generative augmentation methods often treat crack synthesis as a generic image-generation task, offering insufficient control over morphology, boundary fidelity, and scene context. This paper proposes an end-to-end automated pipeline for controllable crack data synthesis that formalizes crack geometry and inspection context into reusable computational constraints. First, procedurally sampled Bézier-curve skeletons are translated into realistic crack masks using a GAN, enabling scalable generation of diverse crack morphologies without manual mask design. Second, a dual-ControlNet diffusion framework disentangles appearance guidance from geometric guidance, with an edge-based branch enforcing strict boundary consistency. The framework supports both background-free synthesis and context-aware inpainting. Experiments on CRACK500 and CrackTree200 show consistent gains over existing augmentation baselines, demonstrating a scalable engineering informatics workflow for automated crack-inspection data generation.
https://arxiv.org/abs/2609.12431
Dementia is a major and growing global health burden, with Alzheimer's disease (AD) accounting for most cases. Timely and accurate diagnosis is central to managing this burden and increasingly depends on integrating complementary clinical and imaging information. Multimodal deep learning can combine these modalities for AD diagnosis, but how its explanations behave across modalities, fusion strategies, and cohorts remains unclear. We developed an explainable multimodal framework pairing a 3D CNN encoder for T1-weighted MRI with a feedforward network for harmonized clinical and demographic data, comparing varied model setups on three-way and pairwise diagnostic tasks using 6,479 internal records from the ADNI and 1,703 independent records from the OASIS-3. On ADNI, the tabular-only model achieved the highest three-class AUC-ROC of 0.879 and best discriminated cognitively normal (CN) versus mild cognitive impairment (MCI; 0.903), while cross-attention performed best for MCI versus AD (0.861); CN versus AD was highly discriminative overall. On OASIS-3, the vision-only model performed best (three-class AUC-ROC 0.910); CN versus MCI remained difficult, and no fusion strategy consistently outperformed single modalities across tasks and cohorts. SHAP and Integrated Gradients identified the MMSE as the dominant tabular feature in both cohorts, with global feature rankings agreeing strongly in ADNI ($\rho=0.94$) and OASIS-3 ($\rho=0.96$); CAM-based explanations, however, changed with model configuration and cohort. These findings show that multimodal performance and explanations are task, modality, fusion, and cohort-dependent: a dominant cognitive signal persisted across cohorts, but feature contributions and CAM explanations did not, underscoring the need to evaluate explainability under cohort shift rather than as a stable, intrinsic property.
https://arxiv.org/abs/2609.12410
Wheat streak mosaic virus (WSMV) is a destructive pathogen of sweet corn and other cereal crops, causing yield losses and complicating early detection because symptoms are spatially variable and subtle. In sweet corn seed production, WSMV also has regulatory importance, as phytosanitary regulations from countries such as New Zealand and Chile require seed lots to be certified virus-free. Visual scouting is unreliable because symptoms can resemble abiotic stress, while enzyme-linked immunosorbent assay (ELISA) is accurate but expensive, labor-intensive, and difficult to scale. We present an automated pipeline for plant-level WSMV detection using unmanned aircraft systems (UAS) multispectral imagery. The framework integrates orthomosaic reconstruction, geospatial alignment, plant extraction, and classification using a Vision Transformer with seven-channel inputs (five spectral bands, NDVI, and NDRE). Using treatment-based labels, the model achieved 89% accuracy on over 6,500 test patches across multiple growth stages. However, ELISA-based ground truth revealed substantial label noise: only a small fraction of sampled plants in inoculated plots were infected. Treatment labels therefore did not reliably represent infection status, and the high accuracy was largely driven by label bias rather than disease detection. Performance decreased markedly against row-level symptom severity and plant-level ELISA labels. Under these higher-fidelity but smaller-sample conditions, both deep learning and classical machine learning showed limited generalization and weak separability between ELISA-confirmed mock-inoculated and infected plants. These results show that UAS-based disease detection is constrained by label fidelity and data availability, emphasizing biologically grounded labels and models aligned with real-world conditions.
https://arxiv.org/abs/2609.12169
Recently, a wide range of recommendation algorithms inspired by deep learning techniques have emerged as the performance leaders on several standard recommendation benchmarks. While these algorithms were built on different DL techniques (e.g., dropouts, autoencoder), they have similar performance and even similar cost functions. This paper studies whether the models' comparable performance are sheer coincidence, or they can be unified under a single framework. We find that all linear performance leaders effectively add only a nuclear-norm based regularizer, or a Frobenius-norm based regularizer. The former ones possess a (surprising) rigid structure that limits the models' predictive power but their solutions are low rank and have closed form. The latter ones are more expressive and more efficient for recommendation but their solutions are either full-rank or require executing hard-to-tune numeric procedures such as ADMM. Along this line of finding, we further propose two low-rank, closed-form solutions, derived from carefully generalizing Frobenius-norm based regularizers. The new solutions get the best of both nuclear-norm and Frobenius-norm world.
https://arxiv.org/abs/2609.11876
Humans and machines often solve harder problems by spending more time on computation. In deep learning, looped models implement this idea during inference by recurrently updating a hidden state. In practice, however, their training backpropagates through only one or a few updates, making it hard to train early updates to support future ones. We propose looped flows, an approach that sidesteps this issue by training the recurrence with local denoising objectives. By imposing temporal association across denoising objectives through progressively decreasing noise levels and shared noise, the model is incentivized to learn recurrent states that transfer useful computation over time, even when gradients cover only a few updates. We then formulate inference as integrating the velocity of a probability flow parameterized by the learned denoiser, coupled with recurrent states. This allows solving harder problems by spending more computation through a finer temporal grid and enables multiple valid predictions from different initial noise samples. Across six reasoning benchmarks including two multi-solution benchmarks, looped flows outperform prior state-of-the-art looped models overall, achieving 58.8% test accuracy on ARC-AGI-1 and 12.2% on ARC-AGI-2.
https://arxiv.org/abs/2609.11801
Reliable, low-latency perception is crucial for Formula Student Driverless vehicles, yet many existing pipelines rely on deep learning and multi-sensor fusion, often requiring GPU acceleration. This paper presents a lightweight LiDAR-only perception pipeline tailored for CPU execution, combining ground removal, IMU-based motion compensation, DBSCAN clustering, and geometric feature-based Random Forest classification. Feature importance analysis reduced the model input from 12 to 7 features while preserving performance. Evaluated on 2,371 labeled clusters collected from real FSD events, the pipeline achieves an F1-score of 98.33% and an end-to-end runtime of 3.13 ms on CPU-only hardware. The released dataset, labeling tool, and trained models provide a practical and reproducible baseline for other resource-constrained autonomous racing teams.
https://arxiv.org/abs/2609.11527
Automated classification of sewer defects is essential for infrastructure condition assessment and maintenance decision-making, but existing deep learning methods struggle to balance classification accuracy and computational complexity in large-scale multi-label scenarios. This study develops Sewer-Transformer-ML, a hierarchical vision Transformer with multi-level feature fusion, together with two lightweight architectures, Sewer-MobileNet-ML and Sewer-Mobile-TransNet, for resource-constrained inspection scenarios. On the Sewer-ML test set, Sewer-Transformer-ML-Base achieved an $F2_{\text{CIW}}$ of 65.68% and an $F1_{\text{Normal}}$ of 92.68%, ranking first on the public leaderboard and exceeding the second-ranked method by 7.6 percentage points in $F2_{\text{CIW}}$. Sewer-MobileNet-ML achieved an $F2_{\text{CIW}}$ of 65.73% with only 17 M parameters, representing an approximately 95% parameter reduction relative to the base model. Under the standard Sewer-Capsule data split, Sewer-Mobile-TransNet achieved 96.43% classification accuracy. When the training set was reduced to 1,177 images, pretraining on Sewer-ML consistently improved model performance. Ablation experiments further showed that direct concatenation was more effective for Transformer features, whereas attention-based fusion better supported multiscale CNN features. These findings provide a computational basis for automated sewer inspection, lightweight model design, and adaptation across civil infrastructure inspection platforms.
https://arxiv.org/abs/2609.11375
Deep learning models, notably Long Short-Term Memory (LSTM), have demonstrated promising performance in channel estimation for high-mobility vehicular environments. However, their black-box nature and architectural overhead limit trustworthiness and efficiency. Classical explainable AI (XAI) methods rely on costly iterative processes, offering only input-level filtering without addressing architectural fine-tuning. To overcome these limitations, this paper proposes the XAI-assisted Recurrent neural network Attribution for Channel Estimation (X-RACE) framework. X-RACE uses a low-complexity, one-shot dual-optimization strategy to simultaneously evaluate and prune irrelevant input subcarriers and internal hidden units. Furthermore, we propose novel temporal XAI metrics: Saturation Time, Importance Drift, and Relevance Contrast to characterize the LSTM's learning dynamics and memory convergence. Extensive simulations demonstrate that X-RACE reduces inference complexity by at least 44.1% while improving or preserving Bit Error Rate (BER) performance, outperforming classical XAI schemes.
https://arxiv.org/abs/2609.11211
Anomaly detection in structured images is challenging in small-data settings where deep learning approaches are costly or impractical. Classical template matching is simple and interpretable but lacks robustness to geometric variations such as scale, rotation, and perspective. We propose a variational template matching framework that represents anomaly templates as a family of transformed instances and performs detection via normalized cross-correlation over this transformation space. To further improve robustness, we introduce a density-based statistical anomaly score derived from local intensity distributions using kernel density estimation (KDE). This produces a smooth representation that captures distributional concentration and tail behavior more robustly than histogram-based methods. The structural and statistical signals are integrated through a unified fusion formulation, enabling complementary modeling of geometric similarity and distributional deviation. Experiments on biological cell images demonstrate that the proposed method outperforms classical baselines and achieves competitive performance with ResNet-50 under a fully training-free setting, while providing explicit localization. The approach offers an efficient, interpretable, and practical solution for anomaly detection in structured image domains.
https://arxiv.org/abs/2609.13298
Label-free virtual staining offers a compelling, non-destructive alternative to standard histopathology; however, its clinical adoption is hindered by the computational bottlenecks inherent to processing gigapixel Whole Slide Images (WSIs). Current deep learning approaches require patch-based inference to avoid memory constraints, which disrupts global tissue continuity and introduces tiling artifacts--displaying visible seams and color shifts. To address this, we introduce the Consistency Memory Bank (COMB), a novel label-free virtual staining framework that enforces spatial and channel consistency across tiles without memory bottlenecks. COMB decouples context storage from computation, utilizing a dynamic retrieval mechanism to fetch feature representations from adjacent tiles. This enables a retrieval-based context integration strategy that adopts local padding to resolve spatial discontinuities and neighbor-aware channel attention to stabilize statistical drift. Further optimized with a sliding window schedule to ensure minimal memory overhead, our method demonstrates superior performance over state-of-the-art baselines, achieving significant improvements in both perceptual fidelity and tiling consistency, while suggesting its downstream utility in tumor segmentation. Code is available at this https URL.
https://arxiv.org/abs/2609.10914
Detecting brain metastases in magnetic resonance imaging (MRI) remains challenging because lesions vary widely in size and appearance, with very small metastases occupying only a minute fraction of a three-dimensional input. We investigate whether combining different spatial fields of view (FOVs) improves lesion detection in multimodal MRI and present a scale-aware 3D deep-learning framework. The method uses independently trained $96^3$ and $64^3$ 3D U-Nets whose whole-volume probability maps are combined by weighted late fusion. This design allows us to study the effect of spatial context separately from image resolution and modality choice. On a 97-patient development cohort, cross-FOV fusion improved lesion-level precision and F1 while substantially reducing false positives relative to the individual models. A same-FOV ensemble control showed that these gains were not explained solely by averaging independently trained networks, supporting a contribution from complementary spatial context. An exploratory cross-FOV agreement filter reduced false positives but did not improve overall F1. These results support cross-FOV probability fusion as a simple and computationally practical strategy for improving the precision-false-positive trade-off in 3D brain-metastasis detection.
https://arxiv.org/abs/2609.10825
The growing reliance on Low-Earth Orbit (LEO) satellite communication systems has increased the need for intelligent methods capable of detecting cyberattacks across complex and dynamic space environments. Unlike conventional network intrusion detection, satellite systems generate heterogeneous information across radio-frequency (RF) links, onboard hardware, and orbital operations. However, many existing approaches either rely on terrestrial intrusion datasets or evaluate individual observations independently, limiting their ability to capture temporal attack behavior specific to LEO satellites. In this work, we conduct a systematic study of deep-learning-based cyberattack detection using the recently introduced satellite-specific UNSW-IoTSAT dataset. We investigate structured learning architectures that preserve hardware, orbital, and RF information, including a Subsystem-Fusion MLP and a hierarchical multimodal Transformer that models both cross-subsystem interactions and temporal evolution. We further evaluate leakage-resistant row-level and temporal settings, along with cross-satellite generalization, to characterize how model architecture and evaluation protocol influence satellite cyberattack detection. Experimental results demonstrate the value of structured multimodal modeling and rigorous evaluation, with the hierarchical Transformer achieving up to 91.66% accuracy and 85.63% macro F1 under the leakage-resistant evaluation protocol.
https://arxiv.org/abs/2609.10746
One-Pixel Attacks (OPAs) represent one of the most extreme demonstrations of adversarial fragility in deep learning, where modifying a single pixel can reliably induce high-confidence misclassification across domains such as medical diagnosis, autonomous driving, biometrics, and quantum communication. Despite their conceptual simplicity, OPAs remain underexamined in existing adversarial-attack surveys, which provide only fragmented or cursory coverage. This PRISMA-guided review synthesizes high-quality studies from 2017 to 2026 and delivers a unified, multi-axis taxonomy of OPA research spanning algorithmic foundations, black-box evolutionary optimization, emerging hybrid and program-synthesis attacks, defence mechanisms, interpretability tools, and domain-specific vulnerabilities. Our analysis reveals the dominance of Differential Evolution-based strategies, the rise of efficiency-optimized and saliency-guided methods, and persistent gaps in dataset diversity, transferability, and standardized evaluation. We summarized and assess defence paradigms including pixel restoration, anomaly detection, input-space transformations, and robust training highlighting their trade-offs in robustness, imperceptibility, and computational overhead. Building on these insights, we outline future research priorities involving selective pixel recovery, transformer-specific vulnerability analysis, saliency-driven optimization, and real-world domain-adaptive defences. We further propose a regulatory framework emphasizing robustness testing, incident disclosure, and AI security governance. This review establishes a comprehensive foundation for understanding, evaluating, and mitigating ultra-sparse adversarial threats in contemporary AI systems.
https://arxiv.org/abs/2610.00125
Nanoscale imaging of mammalian brains is critical for connectomics. X-ray laminography enables high-throughput imaging of extended, plate-like biological specimens. However, the tilted acquisition geometry leads to incomplete Fourier-space coverage, giving rise to a missing-cone of information. Conventional reconstruction methods cannot recover unmeasured information within the cone, resulting in artifacts that distort fine brain structures. While resolving these requires modeling 3D structure, direct 3D deep learning approaches are limited by data scarcity and computational cost. Here we introduce LUCID (Laminography with Unified Consistent Diffusion), a framework that combines multi-view diffusion priors with projection-domain data consistency. LUCID integrates complementary 3D structural information while enforcing strict alignment with the laminography forward model. On simulated datasets, LUCID substantially improves spatial fidelity and restores missing Fourier components, outperforming baseline methods. Applied to experimental laminography data, LUCID generalizes robustly despite being trained exclusively on fully sampled tomographic volumes, and effectively recovers unmeasured Fourier information.
https://arxiv.org/abs/2609.10456
Recent progress in deep learning has significantly advanced facial landmark detection. However, most existing methods process features in a spatial-domain manner under a dataset-specific training paradigm, which overlooks the fact that facial landmark detection is inherently geometry-driven and sensitive to frequency variations, thereby limiting cross-dataset generalization under complex scenarios and hindering the development of a facial landmark detection model. To address this issue, we propose \textbf{FreqFLD}, a \textbf{freq}uency-modulated framework towards All-in-One \textbf{f}acial \textbf{l}andmark \textbf{d}etection. Specifically, FreqFLD introduces a Frequency Modulation Module (FreqMoM) to explicitly induce the frequency prior by decoupling and modulating low- and high-frequency components, which is then injected into subsequent feature modeling to enable balanced modeling of global facial structure and local landmark details. Furthermore, FreqFLD employs a Frequency-Modulated Mixture-of-Experts (FreqMoE), with expert selection adaptively conditioned on frequency-modulated priors, enabling flexible modeling of heterogeneous facial landmark patterns under diverse and challenging scenarios. To regularize frequency-consistent modeling under the All-in-One paradigm, we further introduce a Frequency-Consistent Routing (FreqCR) loss, which constrains the routing and assignment of frequency-aware experts to promote balanced expert utilization across diverse facial scenarios, thereby enabling stable expert specialization and achieving robust facial landmark detection. Extensive experiments demonstrate that the proposed FreqFLD achieves comparable performance on popular datasets. The code is available at: this https URL.
https://arxiv.org/abs/2609.10278
Lung cancer is one of the leading causes of death worldwide, and its early diagnosis is crucial to improving patients prognosis and quality of life. However, the process of interpreting medical images for the detection of lung cancer is complex and requires trained experts. In this context, artificial intelligence (AI) and deep learning (DL) emerge as potential tools to automate and optimize image analysis. The objective of this work is to review the most recent and relevant applications of AI and DL in the field of radiology for the detection of lung cancer. To this end, an exhaustive search was carried out in scientific databases such as PubMed,IEEEXPLORE, Scopus and Web of Science, and 96 articles published from 2015 to the present addressing the use of AI and DL in biomedical engineering were selected. Emphasis is placed on the use of convolutional neural networks (CNN) with transfer learning and Data Augmentation as promising techniques to improve the accuracy and efficiency of the image interpretation process. The results show that the use of AI and DL can offer an effective alternative for the early diagnosis of lung cancer, with high sensitivity and specificity. However, current limitations and challenges that must be addressed to guarantee its responsible and safe application in clinical practice are also identified, such as the lack of standardized data, the ex plainability of the models, patient privacy, and the ethical and social implications. It is concluded that the use of AI and DL can have a positive impact on the care of patients with lung cancer, but further research and regulation are required to ensure its quality and reliability.
https://arxiv.org/abs/2609.10652