Foundation models have recently emerged as a powerful paradigm for learning transferable representations from large scale biomedical data, yet existing approaches for physiological waveforms primarily optimize reconstruction or forecasting objectives that do not explicitly preserve clinically meaningful waveform morphology. Electrocardiograms (ECGs) and pulse oximetry (SpO2) waveforms encode rich cardiovascular and hemodynamic information through their morphological structure. In this work, we introduce MorphologyFM, a multimodal foundation model pretrained on paired ECG and SpO2 waveforms from the MIMIC critical care database using a morphology aware self supervised learning objective. MorphologyFM combines morphology guided masking, cross modal representation learning, and contrastive latent alignment to learn representations that capture clinically relevant physiological structure without requiring manual annotations. We evaluate MorphologyFM across multiple downstream prediction tasks, including arrhythmia classification, hypoxemia prediction, mortality prediction, and length of stay estimation, demonstrating consistent improvements over representative self supervised learning methods, including Masked Autoencoders (MAE), contrastive learning, Barlow Twins, and Joint Embedding Predictive Architectures (JEPA). Furthermore, we show that jointly modeling ECG and SpO2 waveforms produces more transferable representations than single modality pretraining. Our results establish waveform morphology as a powerful inductive bias for self supervised physiological representation learning and introduce MorphologyFM as a general purpose foundation model for continuous physiological monitoring.
https://arxiv.org/abs/2607.09749
Semi-supervised semantic segmentation (SSSS) has long turned on one question, which pseudo-labels to trust, and answered it with ever more careful confidence filtering. Foundation backbones change the regime: with a DINOv2 teacher a strict threshold already retains a measured 98%-clean pseudo-label set, so the accuracy that remains lives not in the filter but in how the embedding space is structured by class. We propose PixCon, a clean-positive pixel-contrastive framework. PixCon maintains a per-class memory bank that admits only labeled pixels the student already classifies correctly, guaranteeing a contamination-free positive set ($\rho_F=0$) by construction, unlike prior contrastive SSSS banks (ReCo, U$^2$PL) built from confidence-filtered pseudo-labels. It is a single branch over a consistency backbone, adds no inference-time parameters, and needs no bank-specific threshold. A first-order analysis of the supervised-InfoNCE gradient explains why contamination hurts: its false-positive term scales as $\rho_F/(1-\rho_F)$, which we measure (0.018 on Pascal, 0.106 on ADE20K) rather than assume. Across Pascal VOC, Cityscapes, and ADE20K, PixCon matches or improves a strong DINOv2-based UniMatch V2 baseline in a compute-matched one-switch protocol: it improves every Pascal-1/8 seed (a per-seed gain of about +0.2 mIoU) and its three-seed mean reaches 87.90, the published UniMatch V2-B figure. Because contamination is already rare under foundation-model teachers, our analysis indicates the $\rho_F=0$ guarantee acts chiefly as robustness as teachers weaken, while the accuracy gain comes from cleaner positive supervision, making clean-positive contrast a robust, low-cost default for foundation-model SSSS.
https://arxiv.org/abs/2607.03068
Active Speaker Detection determines whether a visible person in a video is speaking at each moment. While recent audio-visual fusion methods perform well on clean data, they degrade under real-world corruptions such as background noise, occlusion, or simultaneous modality degradation. We attribute this limitation to the absence of explicit consistency constraints that promote robust, semantically aligned representations across modalities. Without such guidance, models tend to learn fragile modality-specific shortcuts that fail under corrupted conditions. We propose $C^3$ASD, a multi-level consistency-driven framework with three complementary constraints: embedding-level inter-modality consistency aligns audio-visual representations during speech; sequence-level intra-modality consistency separates speaking and non-speaking clusters via track-aware contrastive learning; and prediction-level consistency stabilizes fusion through knowledge distillation. Extensive experiments demonstrate significant improvements under diverse audio, visual and joint corruptions, while maintaining competitive performance on clean data.
https://arxiv.org/abs/2607.03018
Due to the scarcity of expert-annotated data, Semi-Supervised Medical Image Segmentation (SSMIS) has emerged as a promising approach. Many anatomical structures in medical images exhibit significant intra-class heterogeneity, with different regions showing heterogeneous intensity patterns within the same structure. However, existing methods inadequately exploit this intensity-manifested intra-class heterogeneity, resulting in uniform structural representations and imprecise segmentation. Furthermore, the scarcity of labeled data makes it more difficult to effectively capture such complex heterogeneity. To address this, we propose Multiple Prototype Contrastive Learning (MPCL), an SSMIS framework that possesses better diversity and better precision. It consists of three novel designs: First, we provide structural representations with better diversity and propose Intensity-aligned Heterogeneous Prototype Generation (IHPG) that effectively models intra-class heterogeneity by generating multiple prototypes aligned with intensity characteristics. Second, we further enhance more diverse structural representations and build a solid foundation for more precise segmentation through Prototypical Space Optimization (PSO) that systematically optimizes a more discriminative and generalizable prototypical space. Finally, we achieve segmentation results with better precision through Dual-branch Knowledge Alignment (DKA) that efficiently promotes intra-class heterogeneity knowledge transfer from prototypical space to the segmentation network. Extensive experiments on three medical image datasets with significant intra-class heterogeneity demonstrate that MPCL significantly outperforms existing methods, especially under extremely limited labeled data.
https://arxiv.org/abs/2607.02051
Unsupervised cross-modal hashing enables efficient retrieval of semantically related instances across different modalities without requiring manual semantic annotation. However, existing unsupervised methods rely heavily on large-scale image-text pairs. Collecting such data can be costly, particularly in scenarios where well-aligned pairs are scarce due to privacy and specialized constraints. More critically, existing methods tend to overfit to seen training data, restricting their generalization performance on unseen categories that the constrained training data cannot cover. To address these limitations, we propose Attribute-Prompted Kernel Hashing (APKH), a novel data-efficient approach that constructs a compact, modality-aligned Hamming space driven by the generalized attribute priors of vision-language foundation models. Specifically, APKH introduces two core modules: Context-optimized Attribute Kernel Mapping (CAKM) and Kernel-Smoothed Contrastive Alignment (KSCA). CAKM formulates cross-modal alignment through hyperspherical Radial Basis Function kernel mapping, optimizing dynamic attribute kernels via prompt learning to capture modality-invariant semantics. Furthermore, KSCA extends conventional point-to-point contrastive learning by modeling limited paired data as continuous kernel distributions. This explicit smoothing of the modality gap alleviates overfitting to sparse pairwise correlations. Extensive experiments demonstrate that APKH outperforms state-of-the-art hashing methods in the challenging cross-modal retrieval tasks from seen to unseen categories under data-constrained scenarios.
https://arxiv.org/abs/2607.00379
Online Continual Self-Supervised Learning (OCSSL) aims to learn representations from a continuous stream of unlabeled data, without knowledge of task boundaries and under memory constraints. Existing methods rely either on replay buffers that exploit latent space structure, or on regularization alone. We present CLIMB (Continual Learning with Intelligent Memory Bank), which combines both simultaneously. Our method introduces a hierarchical centroid-based memory, bounded in total number of stored images, combined with knowledge distillation on replayed examples to limit representation drift. The memory groups similar images into centroids, providing hard-to-discriminate examples for contrastive learning while covering the diversity of observed distributions. Experiments on Split CIFAR-100 and Split ImageNet-100, on standard benchmarks from the state-of-the-art as well as a new protocol with irregular task distributions show that CLIMB outperforms state-of-the-art OCSSL methods.
https://arxiv.org/abs/2606.31275
Text-Attributed Graphs (TAGs) combine textual semantics with graph structure and are central to many graph learning tasks. However, existing fusion methods often treat text and structure as separate inputs in a shallow, one-way pipeline, which limits deep interaction between modalities and weakens performance under sparse connectivity or cross-graph generalisation. To address this issue, we propose PromptGNN-sim, a bi-directional structure-semantic fusion framework for collaborative GNN-LLM learning. PromptGNN-sim uses a Graph Attention Network (GAT) for semantically aware neighborhood selection by combining structural attention with textual similarity. The selected structural context is then used to generate structure-aware prompts for an LLM, including the target node summary, label categories, and representative keywords from similar neighbors. During training, bi-directional cross-modal contrastive learning and cross-attention are introduced to jointly optimize the GNN and LLM components. Experiments on six public datasets, including Cora, Pubmed, and WikiCS, evaluate accuracy, generalisation, and robustness under cross-task transfer, cross-dataset generalisation, and sparse perturbations. Results show that PromptGNN-sim outperforms classical GNNs, LLMs, and recent GNN-LLM fusion methods, demonstrating the effectiveness of interactive structure-semantic collaboration for text-attributed graph learning.
https://arxiv.org/abs/2606.30291
H&E-stained whole-slide images offer cohort-scale availability and rich spatial context but lack molecular specificity, whereas bulk RNA-seq provides transcriptome-wide resolution at high cost with limited archival availability. We show that training a lightweight alignment module atop frozen histopathology and RNA-Seq foundation models enables open-vocabulary molecular prompting -- querying H&E slides with gene-set signatures to predict pathway activity without sequencing or end-to-end retraining. Using contrastive learning on a multi-cancer cohort (N=1,720), we achieve a 25-fold improvement in retrieval over baseline methods. Systematic analysis reveals a graduated predictability spectrum: morphologically grounded programs (cell-cycle programs, immune-related) are most reliably predicted (R^2>0.5), while predicting pathways with no morphological footprint remains challenging as expected. We validate clinical utility on the POSEIDON clinical trial: H&E-predicted squamous cell carcinoma scores recapitulate NSCLC subtype identity and predicted IFN-gamma mirror PD-L1 tumor-cell expression groups. Furthermore, genesets describing immune activation and fibrosis predict known tumor microenvironment archetypes from histology alone. We further validate generalization of our approach across unseen cohorts and demonstrate data-efficient domain adaptation, establishing a slide-native framework for molecular analysis on H&E images.
https://arxiv.org/abs/2606.29949
Sound event detection (SED) is a core module for acoustic environmental analysis, yet its performance is often limited by scarce labeled data. Recent systems leverage large pretrained audio foundation models, but effective fine-tuning remains challenging because labeled data are limited while unlabeled data are abundant. A previous work, ATST-SED, addressed this problem with a pseudo-label based semi-supervised fine-tuning framework. In this work, we further improve the framework by adopting an embedding-level self-supervised contrastive loss inspired by ATST-Frame pretraining. This contrastive objective better exploits unlabeled data during fine-tuning. One challenge is that mixup serves different roles in the two objectives: pseudo-label learning uses composition mixup, while contrastive learning treats mixup as a perturbation. To resolve this mismatch, we propose conditional mixup, which combines composition mixup and perturbation mixup in one semi-supervised framework and defines the corresponding embedding-level contrastive losses. The resulting model achieves 0.645 PSDS1 and 0.822 PSDS2 on the DESED validation set, establishing a new state of the art.
https://arxiv.org/abs/2606.29901
Recent advances in pathology foundation models have substantially improved patch and slide level representation learning from whole-slide images (WSIs).However, cell-level representations learning remain underexplored, limiting cell resolved interpretability, biological discovery, and clinical translation. We propose CellDETR, a detection-guided framework built on Deformable DETR for scalable cell representation learning from WSIs. By introducing location feature decoupling and box-constrained attention mechanism, CellDETR enables automated extraction of cell-level embeddings, and outperform existing state-of-the-art methods in supervised cell classification on PanNuke data. In addition, by incorporating contrastive learning design, we build a CellDETR-based pretraining model for scalable cell representation learning from unlabeled WSIs, which improves downstream cell classification performance. Furthermore, we show that after pretraining with Xenium spatial transcriptomics-derived cell annotations, CellDETR achieves accurate cross-dataset cell classification, demonstrating the transferability and biological relevance of the learned cell embeddings. Together, CellDETR provides a scalable route toward general cell-level representation learning framework for interpretable computational patholog
https://arxiv.org/abs/2606.29463
Adaptive video streaming is a widely used technique for delivering video content over the internet. One of the key challenges is determining the optimal encoding settings for each video, which can vary significantly based on its content and characteristics. In this paper, we propose Compression Echo Contrastive Learning (CECL), a novel self-supervised learning framework for clustering videos based on their encoding complexity. Our method leverages the response of a video to compression - the Compression Echo - as a supervisory signal, allowing the model to capture underlying encoding characteristics during pretraining. We conduct extensive experiments to demonstrate the effectiveness of our learned representations for the downstream task of clustering videos by their encoding complexity. Our results show that CECL improves upon existing state-of-the-art visual encoders and delivers strong bitrate and quality savings against the fixed bitrate ladder.
https://arxiv.org/abs/2606.29166
Graph-based fraud detection is essential for safeguarding large-scale transaction systems, where undetected anomalies may lead to substantial financial losses and security risks. Real-world fraud graphs pose two coupled challenges: sparse and imbalanced supervision, where verified fraudulent labels are scarce and heavily skewed toward benign accounts, and representation dilution, where spatial message passing may oversmooth camouflaged anomalies while spectral filters may suppress fraud-relevant mid- and high-frequency irregularities. To address these challenges, we propose ADC-GNN, short for Attention-guided Diffusion-Contrastive Graph Neural Network, a unified framework that combines diffusion-guided feature augmentation, contrastive representation learning, and multi-hop spectral attention for few-shot graph fraud detection. The diffusion component is formulated as a feature-space denoising augmentation mechanism rather than a full topology-generative graph diffusion model: it constructs noise-perturbed node-feature views under a cosine schedule and uses contrastive learning to stabilize node representations across perturbations. The spectral attention module further adaptively emphasizes fraud-relevant hop-level and relation-level cues. We evaluate ADC-GNN primarily on three public benchmarks and additionally report a proprietary real-world telecom transaction dataset with approximately 60,000 records as a private case study. Under the 1% training setting, ADC-GNN achieves consistent improvements over original graph fraud baselines and four protocol-consistent recent graph anomaly/fraud baselines on the public benchmarks. Additional analyses on split stability, training ratios, oversampling alternatives, module-level ablations, diffusion schedules, and runtime and memory-consumption comparisons further characterize the effective operating regime of ADC-GNN.
https://arxiv.org/abs/2606.28134
Learning discrete speech representations that preserve similarity across variable-length utterances is central to query-by-example spoken term detection (QbE-STD). While wav2tok introduced CTC-based sequence alignment to enforce token consistency, its tightly coupled clustering and alignment training recipe limits scalability. We propose wav2tok 2.0, a scalable alignment-aware speech tokenizer built on the BEST-STD backbone. wav2tok 2.0 employs staged training, first learning discriminative, speaker-invariant representations via contrastive learning and vector quantization, and then enforcing pairwise token consistency using a CTC alignment loss and a novel DTW-aligned framewise prediction objective with adaptive weighting. Experiments show that wav2tok 2.0 consistently outperforms BEST-STD and general-purpose tokenizers on QbE-STD while remaining efficient and scalable.
https://arxiv.org/abs/2606.26824
Zero-shot tweet-level stance detection confronts two primary challenges: (1) mitigating the context sparsity inherent in short texts, and (2) establishing the relevance between implicit targets and textual content. While existing methods primarily focus on incorporating external knowledge, they neglect the intrinsic semantic cues embedded within key intra-textual entities. Furthermore, current models exhibit limited capability in determining the relevance of unseen targets to the given text, thereby struggling to differentiate between "neutral" and "irrelevant" stance labels. To address these issues, we first construct a four-class, multi-topic Japanese tweet dataset. To our knowledge, this is the first Japanese tweet-level dataset for stance detection. We then propose KIRP, a zero-shot stance detection framework. It integrates external knowledge with entity reorganization for data augmentation and employs prompt chaining for reasoning. Specifically, the framework incorporates knowledge graphs to supplement and reorganize key textual entities, while reflective Chain-of-Thought (CoT) reasoning extracts and validates implicit targets. To better distinguish "neutral" from "irrelevant" labels, we adopt stance-aware contrastive learning to capture discriminative features and design a three-layer iterative prototype network for fine-grained classification. Experimental results on SemEval-2016, WT-WT, and KIRP-D show that KIRP achieves state-of-the-art performance. KIRP obtains F1 scores of 84.05% (three-class) on SemEval-2016, and 84.99% and 79.18% (four-class) on WT-WT and KIRP-D, respectively.
https://arxiv.org/abs/2606.26571
The laser welding full-penetration is of critical importance, as it constitutes one of the fundamental factors in achieving defect-free welded joints. Accurate prediction of the penetration state is therefore essential for ensuring weld quality. To this end, this paper introduces SimPhysNet, a novel algorithm that achieves high classification accuracy in laser welding penetration prediction using only a limited number of labelled images. This approach effectively overcomes the limitations of supervised learning classification algorithms, which are hindered in industrial applications by their dependence on extensive, high-quality labelled data. The core of SimPhysNet is a unique self-supervised learning paradigm that embeds physical priors into a contrastive learning framework. By incorporating a physics-informed neural network (PINN), the model is guided to extract physically meaningful features of the molten pool and keyhole from a large set of unlabelled data, while three image augmentation tasks further enhance its generalization capabilities. Subsequently, a few-shot learning strategy, based on prototypical networks, enables robust classification by constructing class representations from a minimal set of labelled images. Experimental results demonstrate that SimPhysNet achieves a classification accuracy of 96.06% using only 200 labelled images (approximately 5% of the total labelled dataset), which is comparable to the performance of conventional supervised learning algorithms that utilize the entire labelled dataset. This work presents a new, efficient, and highly accurate method, providing the way for the intelligent automation of laser welding.
https://arxiv.org/abs/2606.26059
Zero-shot visual decoding from electroencephalography (EEG) aims to infer visual semantics from non-invasive neural recordings, but remains challenging due to the low signal-to-noise ratio, non-stationarity, and limited spatial resolution of EEG. Existing EEG-vision alignment methods often rely on holistic EEG embeddings, which can obscure the complementary temporal, spectral, and spatial structure underlying visual perception. We introduce a unified multiview EEG representation learning framework for aligning brain responses with visual semantic embeddings. Our method builds an EEG encoder that jointly models three complementary views: input-conditioned state-space temporal dynamics, learnable wavelet-based spectral decomposition for sample-adaptive frequency modeling, and attention-modulated graph learning for structured electrode interactions. The resulting multiview EEG embeddings are fused and aligned with pretrained visual representations in a shared semantic space using contrastive learning with EEG-specific regularization, enabling 200-way zero-shot visual classification. Experiments on THINGS-EEG benchmark show that our method achieves state-of-the-art performance, with 54.8% Top-1 and 85.6% Top-5 accuracy in the within-subject setting and 15.3% Top-1 and 45.4% Top-5 accuracy in the cross-subject setting. We further present the first systematic cross-session EEG-image decoding evaluation, achieving 40.8% Top-1 and 78.0% Top-5 accuracy. These results suggest that explicitly modeling multiview neural structure improves both semantic alignment and generalization in EEG-based visual decoding.
https://arxiv.org/abs/2606.25718
Vision-language pre-training (VLP) holds great promise for general-purpose medical AI by leveraging radiology reports as rich textual supervision, yet existing methods struggle with 3D CT imaging due to inefficient visual backbones and coarse semantic alignment. To address these issues, we propose a tailored VLP framework featuring three key components: (1) a CNN-ViT hybrid encoder that replaces ViT's patch embedding with a 3D CNN backbone to efficiently capture local anatomical details while preserving global attention and compatibility with pre-trained cross-modal priors; (2) a disease-level contrastive learning mechanism using learnable query tokens to dynamically extract disease-specific semantics from full reports and align them with corresponding visual features, thereby disentangling distinct diseases within the same anatomical region; and (3) a diagnosis-aware prompt strategy that employs real clinical phrases and aggregated disease prototypes to bridge the pre-training-inference gap and enhance zero-shot diagnostic reliability. Our model achieves state-of-the-art performance on CT-RATE (84.4% AUC, +5.1%) and Rad-ChestCT (75.4% AUC, +5.4%), with even larger gains (+9.8% AUC) on a challenging 60-disease benchmark, and demonstrates strong transferability to radiology report generation, underscoring the generality and clinical utility of our approach.
https://arxiv.org/abs/2606.25546
Micro-expression recognition (MER) is challenging due to subtle facial movements, limited data, and the ambiguous relationship between Action Units (AUs) and emotion categories. Optical flow and motion magnification have been widely used to describe subtle facial dynamics from different perspectives: the former captures local motion displacement, while the latter amplifies weak appearance changes. In this work, we observe that these two modalities often exhibit asymmetric failure patterns: one modality may become noisy, distorted, or uninformative, while the other still preserves discriminative AU-related evidence. This phenomenon reveals their complementarity, but also raises two key challenges for fusion: cross-modal heterogeneity and spatially varying modality reliability. Motivated by this observation, we propose SAC$^2$-Net, a Semantic Anchoring and Complementary-Consensus Network for multimodal MER, which first aligns visual modalities with semantic anchors and then performs reliability-aware fusion. To reduce cross-modal heterogeneity before fusion, we introduce Semantic Anchoring Soft Alignment (SASA), which converts activated AUs into textual prompts and uses them as stable semantic anchors to align motion-magnified and optical-flow representations. Unlike hard contrastive learning, SASA constructs hierarchical AU-aware soft labels to preserve semantic proximity among samples with overlapping or anatomically related AU patterns. Based on the aligned representations, Complementary-Consensus Fusion (CCF) first repairs unreliable local evidence through complementary exchange and then enforces a shared spatial focus through consensus refinement. Extensive experiments on five MER benchmarks show that SAC$^2$-Net achieves state-of-the-art or highly competitive performance across coarse-grained, fine-grained, large-scale, and cross-dataset evaluation settings.
https://arxiv.org/abs/2606.25542
Ordered bottlenecks aim to provide utility at flexible budgets by assigning coarse information to early tokens and task-relevant detail to later ones. Prior work, including tail dropping (TD), typically enforces ordering by means of a masking-based ordering pressure (MBOP): Late tokens are masked more frequently than early tokens and are therefore encouraged to store less essential fine details. We introduce predictive residual inference for ordered representations (PRIOR), a framework designed to address inherent weaknesses of MBOP. MBOP is prone to weak late-token utility because it lacks an explicit refinement objective and uses gradient exposure as a proxy for importance. Furthermore, representations may become particularly brittle in optimization-sensitive settings, such as when using discrete or quantized token representations. PRIOR replaces activation-rate control with log2-scaled levels and level-wise predictors. These predictors separate already explained from unexplained information, focusing each level on residual error. We compare PRIOR against MBOP-TD and independent tail-biased dropout (MBOP-ITD) in contrastive learning and image reconstruction tasks. Unlike the baselines, PRIOR learns well-ordered representations across experiments: low budgets provide coarse descriptors, while high budgets add refinements. Simultaneously, full-budget performance with PRIOR is higher in all but one experimental setting, where performance remains comparable. MBOP baselines are severely limited in discrete and quantized settings, while PRIOR approaches the performance of continuous counterparts. Taken together, these findings establish PRIOR as an effective framework for ordered representation learning.
https://arxiv.org/abs/2606.25232
Memorization in machine learning models enables high performance on rare in-distribution samples by capturing their atypical patterns. However, it also causes harmful retention of noise and outliers, degrading generalization. While memorization has been extensively studied in both supervised and self-supervised learning in the vision domain, it remains unexplored in multi-modal contrastive learning. We address this gap by introducing MultiMem, the first metric designed to quantify memorization in multi-modal contrastive learning. Through our systematic analysis, we demonstrate that cross-modal semantic misalignment has the strongest influence on memorization, with text being the dominant modality driving memorization, followed by video, image, and audio. We show that targeted augmentations applied across all modalities effectively reduce memorization as measured by our MultiMem metric and improve model performance. Overall, this work establishes the first framework for measuring and mitigating memorization in multi-modal contrastive learning, preventing harmful data retention and contributing to higher-performing models.
https://arxiv.org/abs/2606.22220