Estimating propeller rates from a moving event camera requires separating blade rotation from the changing image geometry. Background activity mixes with blade events, while repeated blade appearances admit half- and double-rate ambiguities. We propose CoHelix, a recursive filter that estimates one shared homography and separate rotation states for four rigidly mounted, coplanar propellers. Each admitted event updates its assigned rotation state, and its accepted geometry measurements correct the shared homography used to interpret later events from every propeller. We report lock, the fraction of evaluated time for which an estimate remains within 2% of synchronized ground truth, because mean error alone does not show how long a tracker follows the true rate. With fixed-rate initialization, leave-one-recording-out evaluation on moving-camera data gives CoHelix 62.9% lock, compared with 39.8% for HelixTrack and 22.2% for EventPro. With other settings fixed, allowing four geometry contributors instead of one raises lock from 3.4% to 62.9%. On a private target-follower dataset with a different target quadcopter, CoHelix retains the measurement settings selected on moving-camera data and uses a fixed initial rate. It reaches 95.9% lock, compared with 56.2% for HelixTrack and 61.1% for EventPro.
https://arxiv.org/abs/2610.31384
While functional magnetic resonance imaging (fMRI) decoders reconstruct images and 3D objects, recovering the metric geometry of rooms from a moving viewpoint remains an open challenge. We introduce, to our knowledge for the first time, the task of reconstructing 3D layouts of held-out scenes using only the known camera trajectories and the fMRI signals of participants watching indoor walkthroughs, without any visual frames. The task is hard because of the temporal mismatch between rapid visual changes and blurred fMRI signals. Our method, DRAFT (Decoding and Reconstructing 3D room lAyouts from fMRI and Trajectories), extracts a compact layout representation from the early visual cortex and fuses this neural code with the geometric free space derived from camera motion. To evaluate it, we propose layout r, the Pearson correlation between predicted and ray-cast log depths. On ten held-out scenes (20 participants), DRAFT reaches a layout r of 0.480, outperforming the camera path alone (0.446) and seven fMRI decoders (at most 0.429). DRAFT also works as a plug-in that improves all seven decoders without retraining, raising their layout r from 0.171-0.429 to 0.487-0.493. Brain activity and camera motion can thus recover the metric layout of unseen rooms, a first step toward reconstructing the 3D spaces people see.
https://arxiv.org/abs/2610.31108
Reproducing a published 3DGS paper takes weeks of expert engineering before any extension can be proposed. Prior autonomous-research systems read papers, draft hypotheses, and write code, but are limited by short fixed templates, low executability, and weak traceability, and none has been demonstrated end-to-end in a live computer-vision subfield with intense activity. SplatLab is an autonomous research system for 3D Gaussian Splatting that addresses these limitations. Given a research prompt, a target-paper URL, or no input at all, it reproduces a published baseline, proposes an extension, trains and ablates across Mip-NeRF 360 and LLFF, writes the manuscript, and binds every reported number to a logged training run. Five design choices distinguish it: (i) candidates mutate plugins from a verified-reproduction backbone matched to published baselines; (ii) a cascade-weighted Elo tournament across eight islands scores candidates on measured GPU PSNR with verbal-gradient feedback; (iii) a standing falsifier subtracts Elo on failure, integrating stress-test survival into selection; (iv) every reported number is bound to a logged training run, and the run cannot terminate while any claim is unbacked; (v) a seven-category 3DGS taxonomy wraps EVOLVE-BLOCK markers in domain-aligned scaffolds transferable across 3DGS repositories. On PSNR-targeted runs, SplatLab's manuscripts beat their reproduced targets by +0.18 to +3.78 dB, including +3.78 dB on astrophotographic nebula rendering, for which no prior 3DGS method exists. The research cycle compresses from months of graduate-student time to days of mostly autonomous compute. Code, all manuscripts, experiment ledgers, and the cross-run paper store are available on the project page.
https://arxiv.org/abs/2610.30468
Radar heart sounds capture cardiac mechanical activity without contact, while echocardiography characterizes ventricular and valvular function. Paired measurements connect these signals to structural heart disease, yet such data remain sparsely represented in public resources. Here we present 537 radar heart-sound recordings paired with one echocardiographic report for each of 162 patients. The cohort covers three overlapping phenotypes: left ventricular ejection fraction (LVEF) below 50%, regional wall-motion abnormality and at least moderate valvular regurgitation, present in 38, 43 and 39 patients, respectively. Original complex signals, processed radar heart sounds and temporal quality segmentation support signal-to-phenotype analysis. Technical validation retains 95.93% of signal duration and confirms reproducible waveform reconstruction. Patient-level five-fold evaluation achieves a mean outer-test AUROC of $0.770\pm0.138$ for reduced LVEF, identifying mechanical information associated with ventricular systolic dysfunction. This resource supports research linking non-contact cardiac mechanical signals to echocardiographic structural and functional phenotypes.
https://arxiv.org/abs/2610.29267
Thermal cameras enable robots to perceive human activities in darkness while revealing less personally identifiable appearance information and fewer details of the surrounding environment than RGB cameras. As vision-language models (VLMs), originally developed for RGB imagery, are increasingly integrated into embodied systems for scene understanding and high-level planning, thermal sensing offers a promising way to extend activity perception to low-light and privacy-sensitive settings. However, the failure modes of VLMs in thermal human activity understanding for human-robot interaction (HRI) remain underexplored. We fill this gap by evaluating seven locally deployable VLMs, including models developed for physical AI and robotics, on two person-centric thermal datasets. Our diagnostic tasks examine fine-grained action recognition, activity timeline reconstruction, and the ability to withhold unsupported answers. Paired RGB recordings serve as a performance reference, while controlled variations in frame sampling, thermal input presentation, and reasoning are used to assess whether the observed errors can be mitigated. Our results show that models can recognize broad activity categories but struggle with fine-grained actions such as coughing, sneezing, and yawning. They also produce inaccurate event timelines and hallucinate actions involving objects. Simple thermal input preprocessing and additional reasoning offer only limited, model-dependent gains. Abstention behavior also varies across models even under explicit instructions, limiting their reliability for practical robotic use.
https://arxiv.org/abs/2610.29244
this http URL distinguish the contributions of acquisition context and photoplethysmography (PPG) to session-calibrated blood pressure (BP) this http URL. The original comparison used three repeats of five-fold participant-level cross-validation in 653 AuroraBP participants, excluding calibration-labelled prediction targets. Matched analyses separated context and PPG and removed elapsed-time terms. Later exploratory follow-ups retained PPG, accelerometer signals and three initial cuff readings. Separate studies evaluated pulse-rate fusion and an intraoperative VitalDB model. Main this http URL original wearable-state model achieved participant-level mean absolute errors (MAEs) of 7.697/6.139 mmHg for systolic/diastolic BP (SBP/DBP). Added context reduced MAE by 0.436/0.126 mmHg (97.5% intervals 0.305-0.573/0.053-0.200). In the matched factorial without the external PPG prior, PPG improved on calibration, time and protocol-provided posture/activity by 0.214/0.135 mmHg; removing time left the DBP interval including zero. Standard PPG descriptors contributed, but additional nonlinear/attractor benefit was not established. In a separate follow-up series, a sensor-history ensemble achieved 7.299/5.445 mmHg versus its static-rich reference's 7.363/5.470, small gains of 0.064/0.025 mmHg. Larger DBP errors did not improve uniformly. Quality-weighted fusion reduced pulse-rate MAE from 3.985 to 3.690 beats per minute. VitalDB MAEs remained 15.375/8.833 mmHg despite small PPG gains. Significance. The contribution is a calibrated evaluation framework with explicit controls, reproducible feature-cache-to-results analyses and retained negative findings. The sensor-history gain is exploratory after repeated dataset reuse. Independently estimated wearable states, complete raw-signal reproduction of the supplied richer features, external transfer and clinical adequacy remain unestablished.
https://arxiv.org/abs/2610.29091
True whole-body medical imaging captures a patient from head to toe and provides comprehensive anatomical and/or functional information. This coverage enables reconstruction of the external body surface, yielding patient body models. However, scanner geometry (e.g., bore diameter), patient characteristics, and positioning can leave body regions missing (e.g., lateral arms/torso, hands, forearms, elbows), producing incomplete patient body models. Such incompleteness limits downstream medical analyses, including derivation of body-habitus metrics (BHMs), such as body volume and surface area, for injected radiotracer activity regimens, cardiometabolic risk assessment, and computational anatomical modeling for medical imaging simulation and radiation dosimetry. We present the Medical Body model Optimization-based Estimator (MedBOE), an automated, training-free framework for estimating complete patient body models from whole-body images with missing body regions. Our innovation is to leverage the Skinned Multi-Person Linear (SMPL) template, a parametric body mesh representing a broad range of body shapes and poses, in medical imaging. MedBOE aligns the SMPL template to the incomplete patient body models via attribute-guided optimization and estimates missing body regions through geometrically and volumetrically constrained deformation. We evaluated MedBOE using two public datasets: AutoPET (91 whole-body PET-CT images) and Human Implicit Tissues (HIT; 40 whole-body segmentations from MRI images). MedBOE achieved the best overall volumetric and geometric performance among evaluated methods. BHMs derived from MedBOE were within 2% error, suggesting low percentage errors for downstream analyses. MedBOE offers an automated, training-free method for estimating complete patient body models from whole-body images with missing body regions.
https://arxiv.org/abs/2610.28985
Wearable devices increasingly support personalized health and well-being applications, but post-deployment data can differ substantially from those used for training, while purely local adaptation may be limited by the data available on a single device during real-world operation. Conventional federated and decentralized learning rely on recurrent communication and stable connectivity, whereas existing opportunistic approaches often exploit available encounters without adequately considering their utility, compatibility, or communication cost. We propose PULSE, an event-driven framework for personalized opportunistic learning that treats each encounter as an online collaboration decision, selecting either no interaction or a promising nearby peer. Peer gradients are incorporated only when compatible with the local learning direction, while past interactions guide future peer selection. Across human activity recognition, fall detection, and stress recognition under synthetic and real contact traces, PULSE preserves or improves personalized classification performance, while reducing peer-assisted exchanges by 80-94% compared with opportunistic model averaging. On-device experiments further demonstrate its feasibility on wearable hardware: peer-assisted operations require limited energy, while the complete implementation occupies 149.8 KiB of RAM and 561.8 KiB of flash. The obtained results show that selective opportunistic collaboration can provide effective personalization while limiting communication and resource demands on constrained wearable devices.
https://arxiv.org/abs/2610.28081
Simulation-ready world reconstruction demands physical interactivity beyond visual realism, which existing black-box 3D generation fails to deliver. We present NeoWorld-3, a coding-agent framework that reconstructs interactive 3D worlds from visual observations via tunable, executable programs. At its core, NeoSDK provides the underlying computational engine for low-level geometries, part composition, differentiable parameter refinement, and physics validation. At the same time, NeoMCP exposes these capabilities as structured, tool-callable APIs for vision-language agents to visually inspect, edit code, and iteratively refine programs. Through a hierarchical coordinator-worker architecture, the framework scales seamlessly from standalone articulated objects to complex compositional scenes. Evaluations across object-level and scene-level reconstruction benchmarks demonstrate that NeoWorld-3 achieves state-of-the-art geometric fidelity and physical readiness. Crucially, manipulation trajectories planned within our reconstructed twins achieve successful zero-shot execution on a physical dual-arm robot, completing the Real-Sim-Real loop.
https://arxiv.org/abs/2610.27690
In robot-assisted education, a robot must understand how to complete a task in order to effectively guide a student through it. We present a novel method that enables a semi-autonomous, camera-equipped robot to recognise the task goal and plan actions to achieve it. Our work focuses on Shoebox Tasks, an activity commonly used in the education of individuals with Autism Spectrum Disorder (ASD). These tasks are designed so that the goal can be inferred directly from their visual structure. We have developed a solver that uses a vision-based Large Language Model to convert photos of a Shoebox Task into a Planning Domain Definition Language (PDDL) representation and generate action plans for solving it. We have also implemented a robotic interface that enables a Nao robot to autonomously execute various Shoebox Tasks and assist a student by suggesting next steps or signalling detected failures through action demonstrations, voice commands, or gestures. With an adapted robotic interface, the solver can be integrated into a variety of educational robots. No programming expertise is required from teachers, and the solver operates exclusively on captured images as input. Research in special educational needs indicates that students with ASD can benefit substantially from robot-assisted teaching, and our system aims to strengthen these learning opportunities while also fostering interest in robotics among individuals with ASD.
https://arxiv.org/abs/2610.27162
Spoken interaction is moving from alternating turns to full-duplex conversation, where an agent listens while speaking. Learning this coordination requires natural dialogue with persistent speaker-resolved tracks, a data requirement that remains difficult to satisfy at scale. Generative recovery offers a route from ordinary recordings, but recovering two voices is not enough: their track assignments can drift as the conversation unfolds. We address this missing link with speaker-anchored routing before diffusion: a 1.84M-parameter module matches the separator's coarse streams to fixed enrollment identities and orders them before a frozen generator reconstructs the speech, without retraining the generator or altering the reconstructed audio. On 25-minute remote conversations, routing cuts wrong-track time from 43.9% to 4.1%, below the 6.2% of matched-enrollment waveform re-identification, with its largest advantage when one participant holds the floor (17.8% versus 28.6%), and raises fixed-track activity F1 from 0.46 to 0.84 while per-chunk reconstruction quality is unchanged. The same router transfers to unseen face-to-face and telephone recordings, and a margin-gated verification step brings their wrong-track time to 0.9-1.7% while embedding 20-36% of the output, where full re-identification embeds all of it. Recovered voices thus become the participant-consistent tracks that full-duplex dialogue modeling needs. Audio examples: this https URL
https://arxiv.org/abs/2610.27109
Histopathology is central to cancer diagnosis, but morphology in Hematoxylin and Eosin (HE)-stained images does not directly reveal the molecular states that characterize disease heterogeneity and inform tumor characterization, prognostic assessment, and biomarker discovery. Spatial Transcriptomics (ST) measures spatially resolved gene expression, providing molecular information within tissue architecture, yet differences in assay coverage and spot informativeness make paired HE--ST observations unequally reliable for representation learning. We propose Reliability-Guided Spatial Transcriptomics (REST) supervision with Biological Program Bank (BPB), a program-structured and reliability-guided ST-supervised training framework for predicting molecular information from H\&E images. REST constructs BPB from curated signature, pathway, and cell-type gene sets to provide a shared structure for ST encoding, reliability estimation, and molecular reconstruction. Guided by BPB, Spot-Reliability Contrastive Alignment (SRCA) measures the reliability of each spot from assay-level program coverage and spot-level activity dispersion, and reweights HE--ST alignment accordingly. Biology-Informed Program Reconstruction (BIPR) further uses learnable program queries to reconstruct member-gene expression from histological morphology. REST's training corpus comprised 209 samples (407,475 spots across 16 organs); evaluation used 70 disjoint samples (230,056 spots across eight organs) for gene-expression, pathway-activity, and cell-signature prediction. REST achieved the highest Macro correlation among state-of-the-art ST-supervised training methods and outperformed existing pathology foundation models. Code is available at this https URL.
https://arxiv.org/abs/2610.26988
Despite breakthroughs in AI-driven molecular generation, existing discovery pipelines operate largely in silico, with wet-lab feedback reserved for validation rather than iterative improvement. Whether large language model (LLM)-based reasoning agents can accelerate de novo discovery by iterating with lab data remains unproven. Here we use protein-binding aptamer design as a sandbox (1-2 week cycles, \$1-\$3 per candidate) to demonstrate a wet lab in a closed loop with AI systems. We tasked agentic pipelines with developing aptamer binders against $\alpha$-thrombin and myoglobin across three design-test-improve cycles ($\sim$1,000 candidates per round; $\sim$4,400 constructs). Statistically significant, bead-corrected on-target hit rates among new candidates rose across rounds from 0.0% in Round 1 to 26.0% in Round 2 and 42.1% in Round 3 on $\alpha$-thrombin (37.1% excluding literature motif descendants), and from 10.2% in Round 1 to 3.7% in Round 2 and 33.5% in Round 3 on myoglobin. Single-clone bead-binding titrations of eight full-length $\alpha$-thrombin candidates confirmed concordance with pooled sequencing enrichment (Pearson $r = 0.90$). In these assays, literature-derived motifs engineered by the agents to reduce off-target reactivity in the pooled screen reached apparent affinities of $K_D = 24.6$--$133$ nM, whereas de novo scaffolds showed low-micromolar binding ($K_D > 1\ \mu$M). We also report how our pipelines used myoglobin binding data to exploit the G-quadruplex binder space, diagnose cross-reactivity as on-target specificity dropped from 75.0% to 19.1%, and recover by developing strategies that restored specificity to 72.4%. We demonstrate that empirical lab data is more valuable than existing computational proxies, showing how iterative experimental feedback enables AI agents to diagnose assay artifacts and refine molecular designs across rounds.
https://arxiv.org/abs/2610.24806
Computational drug discovery requires agents to compose scientific operations and adapt to changing evidence and constraints. Here we introduce DrugHarness, an evolvable agent harness coupling composable scientific execution with conditional skill induction. Its environment integrates over 80 scientific operations, biomedical resources and task-specific code, preserving associations among candidates, results and artifacts. From execution trajectories and outcome feedback, DrugHarness induces action hypotheses with observable applicability conditions, recommended actions and supporting evidence. An independent review agent evaluates candidate skills derived from these hypotheses through source verification and, when needed, targeted execution trials. Admitted skills guide subsequent tasks and are revised through feedback. Evaluation on MolBench and SMDD-Bench demonstrates capabilities in molecular screening, optimization and constrained design. Without evolution, DrugHarness exceeds reported MolClaw-CC results by 10.8 percentage points in affinity-comparison accuracy and 55% in mean top-three active hits on MolBench. Retrospective evaluation on skill-development tasks shows that evolution increases Qwen's affinity-comparison accuracy from 62.2% to 81.1% and optimization success from 79.5% to 87.2%. In a prospective HPK1 study, DrugHarness achieves a more favorable median docking score than Biomni among system-specific candidates. A synthesized compound achieves a cellular IC50 of 14.19 nM, a 2.64-fold potency improvement over the best input reference, with activity competitive with two selected compounds designed by experienced medicinal chemists. These results support conditional skill evolution for scientific agents and demonstrate a workflow connecting computational drug design with experimental validation.
https://arxiv.org/abs/2610.23791
The Italian legislative process is documented in detailed parliamentary records hosted in institutional websites. However, much of this information is available only as unstructured text, limiting its systematic reuse. We applied a controlled, systematic LLM-based extraction procedure, validated against manually annotated records, to convert these texts into ordered and dated events including, e.g., bill introduction, committee examination, plenary examination, and approval. The resulting dataset reconstructs the procedural histories of all 5346 Italian laws enacted between 1985 and 2026, spanning parliamentary terms IX to XIX, for overall 101413 events. Each event records the activity, date, and chamber, with additional procedural details where available. The dataset supports research in the emerging fields of computational legal and legislative studies, potentially combined with process-oriented data science methods to examine procedural paths and legislative timing across parliamentary terms.
https://arxiv.org/abs/2610.23741
Planning while moving faces an historical trade-off between deliberation and reactivity. A planner running concurrently with execution needs time to compute, so the robot must commit to an open-loop action chunk for that duration: a longer commitment buys a better plan at the cost of feedback frequency. Existing controllers fix this action commitment, and consequently the computation budget, before deployment. However, the optimal computation time is highly state-dependent (due to factors such as unmodeled dynamics, safety constraints, and marginal optimisation gains), i.e. dynamic, therefore offline static tuning risks leaving systems blind during critical maneuvers or unable to find global effective solutions. We cast the identification of the optimal computation budget as a semi-Markov decision process (SMDP) in which a single decision defines both the robot action commitments and the time allocated to the solver. To solve this, we train a reinforcement-learning policy conditioned on the current state, the executing plan, and inexpensive planner statistics. Across ground-robot navigation, agile quadrotor flight, and contact-rich manipulation, the learned policy changes its budget with the demands of the scenario, discovering efficient reasoning patterns that outperform fixed-budget baselines. this https URL
https://arxiv.org/abs/2610.23662
Recent speech brain-computer interfaces (BCIs) increasingly rely on large models and complex multi-stage pipelines for neural decoding. However, in speech BCI, where training data are scarce, noisy, and expensive to collect, the benefits of model scaling remain unclear. This work revisits a fundamental question: are large models truly necessary for accurate neural decoding? We propose BEST (Brain-Encoding-Speech-Text), a two-stage framework for efficient neural-to-text decoding. Instead of relying on large generative models or phoneme-centric pipelines, BEST introduces hierarchical intermediate representations and a compact speech-oriented decoder that directly maps neural activity to text. This design preserves essential structure while significantly reducing computational cost, enabling robust generalization in low-resource settings and practical deployment under constrained resources. On the Brain-to-Text '24 and '25 benchmarks, BEST achieves word error rates (WERs) of 6.19% and 1.62%, respectively, using only 3.85% of the parameters required by comparable methods. Beyond these results, we provide three key insights: (1) decoder scaling yields non-monotonic gains; (2) cross-modal alignment is more critical than model size; and (3) overfitting degards sequence-level performance. Representation analysis further reveals a consistent neural-audio-text alignment pathway.
https://arxiv.org/abs/2610.23175
Learning in neural systems arises from synaptic changes that reshape the representations underlying behavior. While low-rank recurrent neural networks (RNNs) have emerged as a powerful framework for linking connectivity to function, a theoretical understanding of their learning process remains elusive. Here, we extend the low-rank framework from activity to learning by deriving gradient-descent dynamics directly in a reduced overlap space. We formulate a closed-form, low-dimensional system of ODEs that governs learning in this space, exact for linear RNNs and asymptotically exact for nonlinear RNNs in the large-$N$ Gaussian limit. Central to our analysis is a distinction between two classes of overlaps: loss-visible overlaps, which fully determine network activity, output, and loss, and loss-invisible overlaps, which do not affect function but are required to describe learning. We illustrate the consequences of this decomposition through two phenomena. First, we show that learning can serve as a perturbation that exposes differences in connectivity between functionally equivalent networks. Second, we show that loss-invisible overlaps can act as memory variables that encode training history, and characterize the conditions under which this occurs. Finally, we present several testable predictions for biological learning experiments derived from our theory.
https://arxiv.org/abs/2605.04115
Online communities provide spaces for individuals navigating stressful life transitions to disclose difficulties and seek peer support. Yet encountering others' distress may also have psychosocial implications for community members. Drawing on stress crossover theory, we examine how engagement with peer distress during graduate admissions is associated with subsequent psychosocial expression and participation, and whether similar associations extend through downstream interactions. We analyze 171,981 posts and 1,130,413 comments from two Reddit communities across three admissions cycles, using propensity-score stratification and baseline-adjusted comparisons. Users who engaged with distress disclosures during application preparation subsequently exhibited higher classifier-estimated anxiety, depression, and stress expression, alongside greater commenting activity and lexical redundancy. These associations recurred across admissions cycles, while no significant psychosocial associations were detected among downstream respondents interacting with previously exposed users. Our findings highlight how greater distress-related expression can coexist with continued community participation, while distinguishing direct engagement with distress disclosures from subsequent social contact. We discuss implications for designing online communities that preserve opportunities for self-disclosure and peer support while remaining attentive to the experiences of those encountering distress-related content.
https://arxiv.org/abs/2610.22657
Understanding characteristics and activities of individuals in complex multi-person environments is crucial for real-world applications. However, existing datasets often simplify this problem to grounded group activity recognition, single-person activity recognition, or close-set activity recognition, thus limiting the generalizability of models trained on these datasets. In this work, we introduce the task of Grounded Human-Attributed Description and Activity Recognition (GHADAR), which involves describing the characteristics and activity descriptions of \textbf{every} person in a video, provided the location of the person in the video, which is more practical for real-world applications. To facilitate this, we introduce a new dataset derived from AVA-Actions by generating open-set captions for the person description and activity. In addition, we propose a novel method to effectively utilize the information contained in grounding during training by constraining the cross-attention masks during training in VLMs to improve performance for this task. Our experiments show that our method outperforms SOTA VLMs on this task. Finally, we demonstrate the limitations of existing evaluation metrics, which are overly reliant on human-annotations and exact text-text matching. As an added video-based evaluation, we propose a holistic VLM-based evaluation schema that compares concepts {\em directly} between the video and the generated predictions. Thus, in this work, we develop a complete framework for GHADAR, including a dataset, a novel method and an evaluation schema, thereby establishing a strong foundation for future research in this domain.
https://arxiv.org/abs/2610.22295