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Unanimously Wrong: Certified Abstention from How Medical LLM Consensus Forms

2026-10-06 00:59:31
Xiaoyang Wang, Tianrui Wang, Christopher C. Yang

Abstract

In clinical practice, agreement among independent experts is treated as evidence of reliability, and multi-round consensus has become a core mechanism of agentic medical question-answering systems. When such a system must decide whether to trust its own answer, the prevailing signal is again agreement, now among the sampled answers. But agreement is a fragile proxy for correctness. A system can be unanimously wrong, returning the same incorrect answer on every sample, and on these questions agreement-based signals carry no information. The cause is that these signals read only the final state of the consensus and discard how it was reached. Agreement that was reached by resolving disagreement with evidence looks identical, at the end, to agreement that was present from the first sample because every sample shares one misconception. ProbeGuard is a certified abstention framework that bases the abstention decision on how the consensus formed. Process features trace agreement trajectories, minority persistence, and retrieval saturation. For unanimous votes, rationale semantic entropy checks whether the reasons behind the vote cohere, and an active probe retrieves counter-evidence and measures whether the consensus survives. A stratified Learn-then-Test calibration then converts these scores into a distribution-free bound on selective risk. We evaluate ProbeGuard on three medical QA benchmarks and a hard-frontier reference, with a published multi-round agentic RAG substrate, against six abstention baselines. On MedQA, 13.4% of unanimous votes are wrong, and no agreement-based signal can flag them. Process signals raise the discrimination of correct from incorrect consensus from chance to 0.696 AUROC. The certified rule answers six in ten unanimous-layer questions at an observed selective risk of 9.0%, and nine in ten once in-domain calibration data accumulate.

Abstract (translated)

URL

https://arxiv.org/abs/2610.07570

PDF

https://arxiv.org/pdf/2610.07570.pdf


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