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Gated Multi-Graph Fusion via Graph Attention Networks for Alzheimer's Disease Detection

2026-06-30 06:15:59
Jinyu Li, Xiao Wei, Bin Wen, Kai Li, Yuqin Lin, Xiaobao Wang, Longbiao Wang, Jianwu Dang
arXiv_AI
               
Abstract

Spontaneous speech is a vital non-invasive biomarker for Alzheimer's Disease (AD), yet many systems overlook non-linear structural disruptions and clinical heterogeneity in pathological language. We propose a Multi-View Gated Graph Attention Network that transcribes audio via Automatic Speech Recognition (ASR) to construct semantic, dependency, and co-occurrence graphs, characterizing speech through a "content-structure-flow" framework. Notably, the co-occurrence graph leverages Pointwise Mutual Information (PMI) from a normative corpus to quantify narrative logic and linguistic deviation. To address symptomatic diversity, an adaptive gated fusion mechanism dynamically integrates these views. Evaluated on the ADReSSo dataset, our model achieves 90.00% accuracy. Ablation results confirm that the PMI-based graph and heterogeneity-aware gating are essential for robust classification across diverse clinical populations. Our source code is publicly available at this https URL.

Abstract (translated)

URL

https://arxiv.org/abs/2606.31186

PDF

https://arxiv.org/pdf/2606.31186.pdf

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